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Autoimmune hepatitis--new aspects of histopathology, ultrastructure and immunohistology

, : Autoimmune hepatitis--new aspects of histopathology, ultrastructure and immunohistology. Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 134(2): 143-151

Auto-immune hepatitis is accompanied by histological and immunohistological peculiarities which have been more thoroughly elucidated in recent time. Predominantly located in portal fields are lymphocytic infiltrations reaching continuously into peripheral lobules. Dendritic reticular cells were recordable from portal fields by electron microscopy. The hepatocytes recorded from peripheral lobules were hydropically swollen and formed microacini. Autoantibodies against components of the hepatocytic membrane seemed to be of relevance to pathogenesis and were recorded from animal experiments. Immunohistologically, the hepatocytic membrane exhibited HLA antigens and IgG. CD 8-positive lymphocytes were detected and were found to be in close contact with liver cells.


PMID: 3048014

Other references

Howe, L., 1909: Tropometers and Measurements of Arcs of Rotation. Transactions of the American Ophthalmological Society 12(Pt 1): 312-319

Jawaid S.M.A.i; Akili W., 2000: Effect of relative density on creep characteristics of sands. Effect of relative density on creep characteristics of saturated dune sands of eastern Saudi Arabia is studied experimentally by conducting drained triaxial creep tests. Dune sand specimens for creep tests were prepared by pluviation compaction th...

Baghdiguian, S.; Verrier, B.; Marvaldi, J.; Fantini, J., 1992: Short-term suramin treatment followed by the removal of the drug induces terminal differentiation of HT29-D4 cells. Suramin is an anti-cancer drug which induces the differentiation of the human colon cancer clone HT29-D4. Yet chronic suramin treatment of these cells eventually leads to a marked disturbance of the lysosomal system, which consists in an accumulat...

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Barbieri, F.D., 1954: Case of heterotypic division in somatic tissue of Telmatobius schreiteri tadpole. Scientia Genetica; Periodico di Genetica Per i Paesi Latini 4(4): 272-274

Fagard, R.; Staessen, J.; Amery, A., 1991: Exercise blood pressure and target organ damage in essential hypertension. To study whether exercise blood pressure is more closely related to the complications of hypertension than resting blood pressure, 169 patients with essential hypertension, aged 16-66 years, (WHO stages I and II), underwent a graded uninterrupted...

Ward G.L., 1971: Nest site preference of chalybion zimmermanni hymenoptera sphecidae. Proceedings of the Indiana Academy of Science 80: 264-266

Xu, X.Z.S.; Sternberg, P.W., 2003: A C. elegans sperm TRP protein required for sperm-egg interactions during fertilization. Fertilization, a critical step in animal reproduction, is triggered by a series of specialized sperm-egg interactions. However, the molecular mechanisms underlying fertilization are not well understood. Here, we identify a sperm-enriched C. elegan...

Nelson, B., 1994: Improving cash flow through benchmarking. Healthcare organizations can use two benchmarking techniques to improve their accounts receivable departments' performance: 1) studying the accounts receivable statistics of model healthcare organizations, and 2) visiting these model organiza...

Khan, E., M.; Lanir, R.; Danielson, A., R.; Goldkorn, T., 2008: Epidermal growth factor receptor exposed to cigarette smoke is aberrandy activated and undergoes perinuclear trafficking. Exposure to hydrogen peroxide (H2O2), one of the reactive oxidants in the gas phase of cigarette smoke (CS), induces aberrant phosphorylation of the epidermal growth factor receptor (EGFR), resulting in the lack of ubiquitination by c-Cbl, and im...