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Bone marrow transplantation in the management of childhood cancer

, : Bone marrow transplantation in the management of childhood cancer. Pediatric Clinics of North America 32(3): 811-833

Bone marrow transplantation has become a curative therapy for selected children with leukemia and offers promise as a treatment for certain childhood solid tumors. Complications such as graft-versus-host disease, interstitial pneumonia, and recurrent malignancy continue to affect many patients. As these are overcome, and as methods for T-cell depletion and marrow purging are developed that extend the scope of bone marrow transplantation, it will become an even more significant therapy for childhood malignancy.


PMID: 3889807

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