+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Bone marrow transplantation in the rat. B lymphocyte activation in acute graft-versus-host disease

, : Bone marrow transplantation in the rat. B lymphocyte activation in acute graft-versus-host disease. Transplantation 41(3): 290-296

We have isolated the white cells from the bone marrow, spleen, and blood of a rat recipient of a bone marrow allograft and the inflammatory leukocytes from the recipient skin, lung, gut, and liver (the parenchymal target organs for acute graft-versus-host disease (aGVHD)) and compared the number of immunoglobulin-synthesizing and releasing cells in these cell populations to corresponding compartments of a syngeneic graft recipient. Bone marrow transplantation was associated in the early phase with marked immunoglobulin production in the cells of bone marrow, spleen, and blood of the allograft recipient; as, however, a similar response occurred in the syngeneic graft recipient we conclude that this is related to reconstitution rather than to aGVHD. Later, during aGVHD, the number of immunoglobulin releasing cells decreased significantly in the spleen and bone marrow of the allografted animal. In clear contrast, in the liver--but not in skin, lung, or gut--very few immunoglobulin-releasing cells were observed in the syngeneic graft recipient, whereas in the allograft recipient a very strong and significantly higher immunoglobulin synthesis and release was seen coinciding with the inflammatory episode of aGVHD in the liver.


PMID: 3513387

Other references

Dermen, Haig, 1936: Fertilization in the Baldwin apple, a triploid variety. The chromosome distribution in the seeds of Baldwin apple, a triploid variety, was studied. The data presented indicate that this variety is self sterile and is easily fertilized by pollen grains of diploid varieties. The mean of chromosome distri...

Feng, W-Sheng.; Pei, Y-Yuan.; Zheng, X-Ke.; Li, C-Ge.; Ke, Y-Ying.; Lv, Y-Yan.; Zhang, Y-Li., 2014: A new kaempferol trioside from Silphium perfoliatum. A new apiose-containing kaempferol trioside, kaempferol-3-O-α-L-rhamnosyl-(1‴ → 6″)-O-β-D-galactopyranosyl-7-O-β-D-apiofuranoside, along with 16 known compounds, were isolated from 50% acetone extract of Silphium perfoliatum L. Their stru...

Anonymous, 2009: An accurate confirmation of human immunodeficiency virus type 1 (HIV-1) and 2 (HIV-2) infections with a dot blot assay using recombinant p24, gp41, gp120 and gp36 antigens. International Journal of Medical Sciences 5(6): 377-377

Kacira, M.; Ling, P.P.; Short, T.H., 2002: Establishing crop water stress index (CWSI) threshold values for early, non-contact detection of plant water stress. Early, non-contact, non-destructive, and quantitative detection of plant water stress with the application of infrared thermometry using a crop water stress index (CWSI) was established. A CWSI model for plants grown under controlled environments...

Anonymous, 1969: What of the future for the young diabetic?. Canadian Journal of Psychiatric Nursing 10(8): 7-8

Chattopadhyay A.; Bhattacharya A.K., 1995: The mineralogy of Beldih apatite, Purulia District, West Bengal. Journal of Mines, Metals and Fuels 43(6): 142-147

Aprasidi G.S.; Khodzhimatov K.Kh, 1989: Wild food dye plants in nura tau range uzbek ssr ussr. Uzbekskii Biologicheskii Zhurnal (6): 29-33

McCormick, C.; Moscovitch, M.; Valiante, T.A.; Cohn, M.; McAndrews, M.Pat., 2017: Different neural routes to autobiographical memory recall in healthy people and individuals with left medial temporal lobe epilepsy. Individuals with medial temporal lobe epilepsy (mTLE) are poor at recalling vivid details from autobiographical memories (AM), instead retrieving gist-like schematic memories. Recent research has suggested that this impoverished recall in comparis...

Arakawa K.; Cyong J C.; Otsuka Y., 1984: Extract of phellodendri cortex antagonizes the hypertensive response induced by heat stress in rats. Japanese Journal of Pharmacology 36(SUPPL): 102P

Lemarchand, E.; Davy, C.A.; Dormieux, L.; Skoczylas, F., 2010: Tortuosity effects in coupled advective transport and mechanical properties of fractured geomaterials. This article is concerned with tortuosity effects in coupled transport and mechanical properties of fractured geomaterials. Experimental results on confined fractured argillite samples are presented in terms of (1) progressive fracture reclosure a...