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Bronchiectasis treated with negative extra-thoracic pressure ventilation

, : Bronchiectasis treated with negative extra-thoracic pressure ventilation. Kokyu to Junkan. Respiration & Circulation 37(5): 559-562

A 25-year old man with 5-year history of bronchiectasis was admitted to the ICU complaining of severe shortness of breath. He had a respiratory rate of 40 to 50 breath/min. On 0.5 l/min of oxygen with nasal cannula, arterial blood pH was 7.39, Paco2 52.3 mmHg, Pao2 45.0 mmHg. Then, on 1 l/min of oxygen, Pao2 was unchanged, but Paco2 increased to 58 mmHg. As his consciousness was so clear, we applied to him the negative extra-thoracic pressure ventilator which was designed by the authors. Negative extra-thoracic pressure ventilation (NETPV) was maintained at a IMV rate of 30 breath/min, peak negative extra-thoracic pressure of -20 to -30 cmH2O, and an inspiratory/expiratory ratio of 1:2. During NETPV, his respiratory rate and oxygen consumption were decreased and Pao2 was increased compared with his spontaneous breathing. He made a recovery from dyspnea, especially, he was able to take a deep breath. When NETPV was applied to him, pulmonary artery and arterial catheterizations revealed that central venous pressure was slightly decreased, cardiac index unchanged or slightly decreased, heart rate, systemic blood pressure, and pulmonary arterial pressure unchanged compared with spontaneous breathing. The patient was able to read books and maintained communication in his voice with his family and the medical staff. After 3 days of the treatment with NETPV, a marked improvement was noted and the patient was discharged from the ICU. NETPV has the benefits as follows. First, it is very easy for both a patient and a doctor to assist his breathing because an endotracheal intubation is not necessary.


PMID: 2749017

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Patel, C.K.; Berg, S.J.; Quaghebeur, G.; Richards, P.; Kamalden, T.A.; Brennan, R.; Elliot, A.; Kafil-Hussain, N.; Williams, C.; Worthington, V., 2012: Ectopic cerebrospinal-like fluid from retrobulbar cysts as a possible cause of pediatric retinal detachment associated with optic disc coloboma: new implications for management. Archives of Ophthalmology 130(8): 1065-1067

Abe, T.; Ohashi, T.; Tamai, M., 1998: Expression of cytokine genes in a patient with conjunctival melanoma compared with other pigment cells. Conjunctival melanomas, which have a relatively good prognosis as compared to other mucosal melanomas, have been investigated morphologically and pathologically. We examined the gene expression of several cytokines in a patient with conjunctival m...

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Laamanen, U.; Tiekso, J.; Koski, K., 1993: Trigeminal foraminal patterns in "skeletal" Class II and Class III adults--a radiocephalometric study. Radiocephalometric analysis, based mainly on the foramina of the trigeminal nerve branches, was applied to three samples of adults, two representing fairly extreme profile types, the third representing "normal" dentofacial build. The aim...

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Devenish, R.J.; Newlon, C.S., 1982: Isolation and characterization of yeast ring chromosome III by a method applicable to other circular DNAs. A method is described for the isolation and purification of covalently closed circular (ccc) DNA from yeast (Saccharomyces cerevisiae). Spheroplasts are lysed at pH 12.45 which denatures linear but not ccc DNA. Next, the lysate is taken through a...

Watson, H., 1956: Delayed prothrombin estimation in outpatient anticoagulant therapy. Lancet 270(6922): 541-543