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Characterization of the transport of the nonelectrolyte dimethyl methylphosphonate across the red cell membrane

, : Characterization of the transport of the nonelectrolyte dimethyl methylphosphonate across the red cell membrane. Nmr in Biomedicine 1(4): 198-204

We have refined the method for measuring the equilibrium exchange of the neutral phosphoryl compound dimethyl methylphosphonate across the human red cell membrane using 31P NMR spectroscopy. Using this improved technique we measured a permeability coefficient of dimethyl methylphosphonate of 9.47 +/- 1.01 X 10(-5) cm s-1 at a concentration of 164 mM, at 25 degrees C. The transport at 25 degrees C was not saturable up to a concentration of 600 mM and was not inhibited by 4,4'-diisothiocyano-2,2'-disulfonic acid, p-chloromercuriphenyl sulfonic acid, copper ions or phloretin, or by thiourea or urea at 16 degrees C. The permeability was enhanced by butanol and phloretin.


PMID: 2641286

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Semple, K.T.; Dew, N.M.; Doick, K.J.; Rhodes, A.H., 2005: Can microbial mineralization be used to estimate microbial availability of organic contaminants in soil?. The aim of this study was to characterize the behaviour of a PAH-degrading bacterium to determine whether mineralization plateaus as a result of substrate removal, a decrease in microbial activity or nutrient availability in sterile soils over tim...

Anonymous, 1968: Tropical Institute for Animal Breeding and Veterinary Medicine in Tropical Countries. Central African Department of Veterinary and Zoological Research, Fort Lamy. Annual Report, 1967, Vols. 1, 3 & 5. Investigations reported include: lists and incidence of helminths of livestock, dromedaries, zebu, elephants and game animals (including a check list of the latter); oribatid mites as vectors of Moniezia expansa, Avitellina centripunctata and Stil...

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Williamson J.R.; Steenbergen C.; Deleeuw G.; Rich T., 1976: Mechanisms of ischemic damage in cardiac muscle. Federation Proceedings 35(7): 1975

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Park S.; Randall L.L., 1989: Comparison of conformation of purified ribose binding proteins either export competent or export incompetent produced in escherichia coli. Three alleles of rbsB gene including export defective mutant were cloned for overproduction of proteins. Five different species of precursor and mature ribose-binding proteins were purified to homogeneity. The purified proteins were subjected to a...

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Szurdoki, F.; Ward, B.; Gee, S.J.; Hammock, B.D.; Gilchrist, D.G., 1996: Synthesis of protein conjugates and development of immunoassays for fumonisins. Abstracts of Papers American Chemical Society 211(1-2): ENVR 42

Abdullokhodzhaev, Z.Ia.; Bronshteĭn, A.Ia.; Levinzon, E.N.; Khashimova, P.R., 1986: Prognostic value of determining circulating immune complexes after acute viral hepatitis B of children. Laboratornoe Delo: 35-37