+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Crystallization and preliminary characterization of three crystal forms of human recombinant transforming growth factor-alpha

, : Crystallization and preliminary characterization of three crystal forms of human recombinant transforming growth factor-alpha. Biochemical and Biophysical Research Communications 187(1): 146-151

Three crystal forms of human recombinant TGF-alpha have been grown from solutions containing 2-methyl-2,4-pentanediol. One of the forms belongs to the orthorhombic space group C222(1) and the other two belong to the monoclinic space group C2. Two of the crystal forms diffract to approximately 2.3 A Bragg spacings. X-ray diffraction data has been collected for all three forms. These data appear to be suitable for crystal structure determination, using either heavy atom isomorphous replacement methods or molecular replacement, for phase determination.


PMID: 1520295

Other references

Thomadaki, H.; Tsiapalis, C.Milto.; Scorilas, A., 2007: The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines. Purpose Posttranscriptional modifications, such as polyadenylation, are very often implicated in the regulation and dysregulation of cell death, through regulation of the expression of specific genes. Based on the fact that an increasing number of...

McRORIE.R.A.; NOVELLI.G.D., 1958: Glucuronate metabolism by Aerobacter aerogenes. Nature 182(4648): 1504-1505

Cernohorský, J., 1979: Automaticity of the abnormal atrioventricular junction in WPW syndrome. Vnitrni Lekarstvi 25(11): 1041-1047

Chmielewski, T.; Szymanek, A.; Mączka, I.; Fiecek, B.; Simon, K.; Tylewska-Wierzbanowska, Sława., 2014: Case report of African tick-bite fever from Poland. A confirmed case of rickettsiosis acquired in South Africa and recognized in Poland was described. The patient fulfilled clinical criteria highly suggestive of African tick bite fever, such as eschars, regional lymphadenitis, cutaneous rash within...

Schneider-Ohrum, K.; Cayatte, C.; Bennett, A.Snell.; Rajani, G.Manohar.; McTamney, P.; Nacel, K.; Hostetler, L.; Cheng, L.; Ren, K.; O'Day, T.; Prince, G.A.; McCarthy, M.P., 2017: Immunization with Low Doses of Recombinant Postfusion or Prefusion Respiratory Syncytial Virus F Primes for Vaccine-Enhanced Disease in the Cotton Rat Model Independently of the Presence of a Th1-Biasing (GLA-SE) or Th2-Biasing (Alum) Adjuvant. Respiratory syncytial virus (RSV) infection of children previously immunized with a nonlive, formalin-inactivated (FI)-RSV vaccine has been associated with serious enhanced respiratory disease (ERD). Consequently, detailed studies of potential ERD...

Graham, S.L.; Klistorner, A.I.; Goldberg, I.; Billson, F.C., 2001: A new method of multifocal objective VEP perimetry for glaucoma detection. IOVS 42(4): S314, March 15

Antonovics, J.; Bradshaw, A.D.; Turner, R.G., 1971: Heavy metal tolerance in plants. Within this review one section is devoted to the genetics of heavy-metal tolerance and others to relevant geographical, taxonomic and ecological investigations, mechanisms of heavy metal tolerance and practical applications.

Mohler, M.M., 1999: Congress hears about malnutrition in nursing homes and the influence of staffing. Director 6(2): 73-74

Sawant, K.V.; Xu, R.; Cox, R.; Hawkins, H.; Sbrana, E.; Kolli, D.; Garofalo, R.P.; Rajarathnam, K., 2016: Chemokine CXCL1-Mediated Neutrophil Trafficking in the Lung: Role of CXCR2 Activation. The chemokine CXCL1 and its receptor CXCR2 play a crucial role in host immune response by recruiting and activating neutrophils for microbial killing at the tissue site. Dysregulation in this process has been implicated in collateral tissue damage...

Lauryssen, C.; Jackson, R.J.; Baron, J.M.; Tallarico, R.A.; Lavelle, W.F.; Deutsch, H.; Block, J.E.; Geisler, F.H., 2016: Stand-alone interspinous spacer versus decompressive laminectomy for treatment of lumbar spinal stenosis. To compare the two-year clinical outcomes of a prospective, randomized controlled trial of an FDA-approved interspinous spacer with the compilation of published findings from 19 studies of decompressive laminectomy for the treatment of lumbar spin...