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Cystic fibrosis, Crohn's colitis, and adult meconium ileus equivalent

, : Cystic fibrosis, Crohn's colitis, and adult meconium ileus equivalent. Diseases of the Colon and Rectum 29(9): 567-571

A 23-year-old man with cystic fibrosis developed massive rectal bleeding that continued intermittently, necessitating an emergency laparotomy and total colectomy. The resected colon was shortened by fibrosis and displayed widespread excessive production of mucus, forming a carpetlike layer over the mucosa as well as segmental discrete areas of mucosal ulceration with fissures, transmural inflammation, and multiple epithelioid granulomas, which are in keeping with Crohn's disease. One case, in a seven-year-old girl, had been reported previously.


PMID: 3488886

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Claude, J.R., 1999: Safety of medications. Safety evaluation is an essential part for the registration of new drugs. Animal studies are performed to assess toxicity by single and repeated dose administration, potential effects on reproduction, genotoxicity, carcinogenic potential and local...

Johansson, R.S., 1978: Tactile sensibility in the human hand: receptive field characteristics of mechanoreceptive units in the glabrous skin area. 1. Impulses in tactile units innervating the glabrous skin of the hand recorded from the median nerve of adult human subjects. The recording electrodes which were made of tungsten were inserted percutaneously in the upper arm. 2. The units were cl...

Vesely, R., 2011: Taking it ot the next level. As reform settles in and economic woes wear on, the Top Women in Healthcare keep moving forward. As the effects of reform start to settle in, the Top 25 Women in Healthcare are helping show how integral changes can be made to the system. "They clearly understand the vision. They asked me to be bold," says Dr. Tracy Gaudet, left, say...

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Sanchez, O.; Mas, J., 1996: Measurement of light absorption and determination of the specific rate of light uptake in cultures of phototrophic microorganisms. This article describes a novel method for the measurement of light absorption by cultures of phototrophic microorganisms. The rate of light absorption is calculated as the difference between the rate of light output from a culture containing cells...