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Effects of thyroxine pretreatment and calcium on the isolated perfused rat heart


, : Effects of thyroxine pretreatment and calcium on the isolated perfused rat heart. Archives Internationales de Pharmacodynamie et de Therapie 221(2): 180-189

Phosphorylase a activity was the same in isolated perfused hearts from euthyroid and thyroxine-pretreated rats. Perfusion with 3.6 mM Ca2+ caused an increase in phosphorylase a in hearts from euthyroid as well as those from thyroxine-pretreated animals, but the Ca2+-induced stimulation of phosphorylase activity was similar in both groups over the time course studied. Greater conversion of phosphorylase b to a occurred with 7.2 mM than with 3.6 mM Ca2+ in both groups, but once again thyroxine pretreatment did not significantly influence the conversion of phosphorylase b to a. Isometric systolic tension increased in response to 3.6 mM and 7.2 mM Ca2+ in hearts from normal and thyrotoxic rats, but thyroxine pretreatment did not appreciably alter the nature of this response. While spontaneous heart rate was higher in hearts from thyroxine-pretreated rats, perfusion with 3.6 mM or 7.2 mM Ca2+ had no significant effect on heart rate in hearts from euthyroid or thyrotoxic rats.

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PMID: 962434


Other references

Jin, Z.W.; You, J.X.; He, W.L., 1990: Studies on new wood preservatives. Results are given of studies on copper compounds and ammoniacal copper compounds used in China.

Wood, S.A.; Kirby, B.M.; Goodwin, C.M.; L.R.es, M.; Meyers, P.R., 2006: PCR screening reveals unexpected antibiotic biosynthetic potential in Amycolatopsis sp. strain UM16. Aims: To assess the antibiotic biosynthetic potential of Amycolatopsis sp. strain UM16 and eight other Amycolatopsis species.Methods and Results: Amycolatopsis genomic DNA was screened by PCR for the glycopeptide, Type-II (aromatic) polyketide an...

Ford, E.J.H.; Boyd, J.W., 1960: Some observations on bovine aceto-naemia. Changes in the liver, in blood ketone and sugar levels and in certain serum enzymes are reported for 5 cases of acetonaemia in dairy cows. The changes in blood and liver often persisted after the clinical symptoms had disappeared. It is thought th...

Zvalinskii V.I.; Litvin F.F., 1988: Modelling of photosynthesis and associated processes. Biophysics (English Translation of Biofizika) 33(1): 183-199

Munyer, T.P.; Margulis, A.R., 1981: Ruptured bronchus. Ajr. American Journal of Roentgenology 136(5): 1028-1029

Fox, C.A.; McConnell, K.H., 2004: Toward biochemical understanding of a transcriptionally silenced chromosomal domain in Saccharomyces cerevisiae. Epithelioid haemangioendothelioma (EHE) is a rare vascular tumour of intermediate behaviour. It can arise from various sites including the liver, spleen, pleura, or lung. Cutaneous EHE can be primary or secondary. This report describes the case of...

Hodes, R.; Gribetz, I., 1962: H-reflexes in normal human infants: depression of these electrically induced reflexes (EIR's) in sleep. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine 110: 577-580

Unni K.K.; Kottke B.A.; Titus J.L.; Brown A.L.; Wallace R.B., 1974: Pathology of aorto coronary saphenous vein grafts. Laboratory Investigation 30(3): 391

Marchal R.; Metche M.; Vandecasteele J P., 1980: Intra cellular concentrations of citric acid and iso citric acid in cultures of the citric acid excreting yeast saccharomycopsis lipolytica grown on alkanes. The intracellular concentrations of citric and isocitric acids were very low for most of the growth cycle of S. lipolytica on alkanes. They increased linearly during the phase of acid excretion and the intracellular concentration was similar to th...

Carnmalm, B.; Jacupovic, E.; Johansson, L.; de Paulis, T.; Rämsby, S.; Stjernström, N.E.; Renyi, A.L.; Ross, S.B.; Ogren, S.O., 1974: Antidepressant agents. 1. Chemistry and pharmacology of amino-substituted spiro(5H-dibenzo(a,d)cycloheptene-5,1'-cycloalkanes). Journal of Medicinal Chemistry 17(1): 65-72