+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Endothelin-1-like immunoreactivity in human urine

, : Endothelin-1-like immunoreactivity in human urine. Nephron 57(1): 36-39

By using a radioimmunoassay specific for endothelin-1 (ET-1), we studied whether ET-1-like immunoreactivity (LI) is present in human urine. Significant amounts of ET-1-LI were present in human urine, and the daily urinary excretion of ET-1-LI in 30 normal subjects was 67.6 +/- 35.5 ng/day. The mean urinary excretion of ET-1-LI determined in spot urine was 82.8 +/- 38.2 pg/mg creatinine (n = 30), while the mean plasma concentrations of ET-1-LI in the same individuals were 1.1 +/- 0.5 pg/ml. There was no significant correlation between urinary ET-1-LI excretion and its plasma levels. Reverse-phase high-pressure liquid chromatography of human urine extract revealed a major ET-1-LI component coeluting with standard ET-1. The present study demonstrates the presence of ET-1-LI excreted in human urine, although its exact source and physiological significance in renal tissues remain to be determined.


PMID: 2046813

Other references

Buchholz, R.; Neef, G.; Glück, S., 1983: Experiences with the metroplasty. Report on 34 metroplasties between 1955 and 1980 at the women's hospital in Halle. 20 patients postoperatively delivered 24 children. One patient is pregnant at present. There were 6 abortions. A spontaneous delivery is possible if there are...

Nerurkar, M.G.; Waingankar, V.S.; Malani, R.G.; Bhalerao, R.A., 1974: Natural spleno-renal shunt. Journal of Postgraduate Medicine 20(3): 129-131

Mieno, T.; Kitamura, S., 1989: Incidence of pulmonary thromboembolism in Japan. Kokyu to Junkan. Respiration & Circulation 37(9): 923-927

Neville, S.; Mookerjee, L.; Guertin, L.A., 2011: Uses of existing GigaPan images in the Earth and space science classroom. Classroom teachers are consistently faced with the challenge of getting students out of the classroom and engaged with field studies in their physical environment. Teachers may also have difficulty getting students to museums to explore classic sp...

Fraser, C.E.; Petrakos, P.; Lelli, G.J., 2013: Adjunctive re-dilation for early cicatrization after punctoplasty. To evaluate punctoplasty outcomes with adjunctive in-office probing of early post-procedure cicatricial changes. Retrospective analysis of all eyes undergoing 3-snip punctoplasty by a single surgeon between August 1,2008 and June 30, 2011. Twenty-...

Hampton, I.F., 1969: Effect of cold exposure in the Antarctic on heat elimination from the hands. Federation Proceedings 28(3): 1129-1134

Vooren, J. van de; Lint, P.J.A.L. de; Challa, H., 1978: Influence of varying night temperatures on a cucumber crop. In: Potential productivity in protected cultivation. A cucumber winter crop, with 4 planting dates, was grown with different night temperatures : 12 deg C, 16 deg C, 20 deg C, or with 5 or 10 hours at 20 deg C and the rest of the night 12 deg C. Day temperatures were the same in all treatments. Clim...

Rebello, A., 1954: Ophthalmological indexes in the Brazilian armed forces. Arquivos Brasileiros de Medicina Naval 15(51): 3215-3230

Mantel, K., 1935: The combination of pedigree lines. POULTRY recording is now uniform throughout Germany, thus removing any ambiguity in respect of such terms as laying year, winter egg production, average egg weight, and selection results. Breeders are advised to breed pedigree lines until the enti...

Gao, L.; Li, D.; Gao, F.; Liu, Z.; Hou, Y.; Chen, S.; Zhang, D., 2015: Hydroxyl radical-aided thermal pretreatment of algal biomass for enhanced biodegradability. Algal biomass, known as a potential feedstock for biofuel production, has cell wall structures that differ from terrestrial biomass. The existing methods for processing algae are limited to conventional pretreatments for terrestrial biomass. In th...