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Evidence that combined thromboxane A2 and serotonin receptor blockade might prevent coronary artery thrombosis and the conversion from chronic to acute coronary heart disease syndromes


, : Evidence that combined thromboxane A2 and serotonin receptor blockade might prevent coronary artery thrombosis and the conversion from chronic to acute coronary heart disease syndromes. Blood Coagulation & Fibrinolysis 1(2): 211-218

Evidence that combined thromboxane A2 and serotonin blockade may prevent coronary artery thrombosis and the conversion from chronic to acute coronary heart disease syndromes is considered. Available data from clinical and experimental animal studies are consistent with the hypothesis that interference with thromboxane and serotonin's contributions to platelet aggregation and dynamic coronary artery constriction might prevent the conversion from chronic to acute disorders, including the development of unstable angina and myocardial infarction in some patients at risk. Substantial protection preventing the conversion from stable to unstable angina and myocardial infarction may very well require both thromboxane and serotonin receptor antagonists or the combination of a thromboxane synthesis inhibitor and receptor antagonist with a serotonin receptor antagonist. Future clinical studies should test this hypothesis directly.

US$29.90

PMID: 2130933


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Pratt, S.D., 2012: Recent trends in simulation for obstetric anesthesia. The use of simulation in medicine has grown significantly over the past 2 decades. Simulation in obstetric anesthesia can be divided into four broad uses: technical skills, nontechnical or teamwork skills, individual clinical competence, and the s...

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Griebel, G.; Blanchard, D.C.; Blanchard, R.J., 1996: Evidence that the behaviors in the Mouse Defense Test Battery relate to different emotional states: a factor analytic study. The Mouse Defense Test Battery (MDTB) has been designed to investigate defensive responses of Swiss-Webster mice confronted with a natural threat, a rat. These behaviors include flight, avoidance, defensive threat/attack reactions, and risk assess...

Cortini Pedrotti C., 1976: Drepanocladus exannulatus subvar glaciale in lake monte cengello eastern trentino. Studi Trentini di Scienze Naturali Sezione B Biologica 53(6): 215-216

Paris W.C.J.; Berry R.M., 1984: Considerations for bench mark subsidence monitoring. Bulletin of the Association of Engineering Geologists 21(2): 207-213

Shugart, Y.Y.o; Ott, J., 1996: An empirical approach to distinguish true and false positive lodscore peaks. European Journal of Human Genetics 4(SUPPL 1): 14

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Rudolf, K.; Rudolf, H.; Töwe, J., 1982: The indocyanine green (Ujoviridin) test in patients with hyperemesis gravidarum. A dose of 0.5 mg/kg body weight of indocyanine-green (Ujoviridin), a chromodiagnostic, was applied in one single injection under standardised conditions to 16 patients, aged between 21 and 31 years (25.9 years on average), with slight to moderate...

Assaf, B.A.; Ebersole, J.S., 1997: Continuous source imaging of scalp ictal rhythms in temporal lobe epilepsy. Purpose: We wished to determine whether continuous EEG source imaging can predict the location of seizure onset with sublobar accuracy in temporal lobe epilepsy (TLE). Methods: We retrospectively analyzed the earliest scalp ictal rhythms, recorded...