+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Expression of preproenkephalin-like mRNA and its peptide products in mammalian testis and ovary

, : Expression of preproenkephalin-like mRNA and its peptide products in mammalian testis and ovary. Proceedings of the National Academy of Sciences of the United States of America 82(21): 7467-7469

The distribution of preproenkephalin mRNA and proenkephalin-derived peptides have been examined in gonadal tissues from rats, hamsters, and cattle. A preproenkephalin mRNA band was detected in the ovaries of all three species and in hamster testis that is identical in size to the 1450-nucleotide mRNA typically found in tissues that express proenkephalin. Rat testis, on the other hand, expresses at least one preproenkephalin-like mRNA that is substantially greater in size (1900 nucleotides). [Met]enkephalin-containing peptides were also detected in each of the gonadal tissues examined. Although the abundance of preproenkephalin-like mRNA in rat testis was comparable to that in rat brain, the testicular content of proenkephalin-derived [Met]enkephalin sequences was less than 4% of the rat brain content. Together these data suggest that preproenkephalin-like mRNA in rat testis is not efficiently translated, proenkephalin-derived peptides undergo rapid turnover in this tissue, or the mRNA in rat testis has a frameshift resulting in an altered coding sequence.


PMID: 3864164

Other references

Krakauer, N.Y.; Grossberg, M.D.; Gladkova, I.; Aizenman, H., 2013: Information Content of Seasonal Forecasts in a Changing Climate. We study the potential value to stakeholders of probabilistic long-term forecasts, as quantifiedby the mean information gain of the forecast compared to climatology. We use as a case study theUSA Climate Prediction Center (CPC) forecasts of 3-mont...

Sal, D.E.; Gregory, D.D., 1981: Can hospitals succeed at self-insuring employees?. Hospital Financial Management 35(4): 14-18

Jilek, C.; Krenn, M.; Sebah, D.; Obermeier, R.; Braune, A.; Kehl, V.; Schroll, S.; Montalvan, S.; Riegger, Günter.A.J.; Pfeifer, M.; Arzt, M., 2011: Prognostic impact of sleep disordered breathing and its treatment in heart failure: an observational study. Sleep disordered breathing (SDB) may contribute to disease progression in patients with chronic heart failure (CHF). The objective of this observational study was to evaluate whether SDB is a risk factor for mortality in CHF patients and whether t...

Cadez, R.; Früh, B.; Böhnke, M., 1998: Quantification of intrastromal micro-deposits in long-term contact lens patients. Some months ago we described morphological changes in the stroma of the cornea of patients with a history of long term contact lens wear. These degenerations consist of little highly reflective structures called "micro-dots". For a more...

Gonzalez, Y.M.; Grossi, S.G.; D.N.rdin, A.; Dunford, R.G.; Machtei, E.E.; Genco, R.J., 1993: Correlation between serum levels of cotinine and periodontal attachment loss. Journal of Dental Research 72(ABSTR SPEC ISSUE): 332

Andriiashkin, A.V.; Vasil'ev, V.E., 2007: Surgical treatment of iatrogenic thrombosis of femoral vein after hernioplasty. Khirurgiia: 63-64

Hashimoto, T., 1955: Experimental studies on the mechanism of infection and immunity in tuberculosis from the standpoint of analysis of streptomycin dependent tubercle bacilli. 4. Immunization against tuberculosis in guinea pigs with a streptomycin-dependent mutant. Kekkaku 30(12): 707-711

Hawes, I.; Schwarz, A.-Maree, 1996: Epiphytes from a deep-water characean meadow in an oligotrophic New Zealand lake: Species composition, biomass and photosynthesis. 1. The epiphytic flora of a characean meadow in Lake Coleridge, a deep, oligotrophic lake on the South Island of New Zealand, was dominated by diatoms, particularly Eunotia pectinalis and Achnanthes minutissima. The meadows occupied a depth range...

Previgliano, V.; Monfrin, S.Barone.; Notaro, V.; Preti, G., 2007: A new coping for overdentures. Part 1: A pilot study of the marginal precision. The aim of this study was to investigate the marginal precision of new chairside copings prepared on 20 extracted teeth. The marginal fit was examined microscopically through 360-degree external observations. Subsequently, 10 new copings were adap...

Piatrauskene, I.I., 1983: Effectiveness of dispensarization of patients with hypertension. Sovetskoe Zdravookhranenie: 20-22