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Fatal iron intoxication with multiple coagulation defects and degradation of factor VIII and factor XIII


, : Fatal iron intoxication with multiple coagulation defects and degradation of factor VIII and factor XIII. Scandinavian Journal of Haematology 22(3): 235-240

A severe iron intoxication in a 15-year-old girl resulted in profound damage to vital organs and multiple clotting defects, but no haemorrhagic diathesis. Investigation revealed not only impaired synthesis of coagulation factors but also abnormal proteolysis by plasmin as well as by other proteolytic enzymes liberated from leucocytes and damaged tissue cells affecting especially factor VIII and factor XIII.

US$29.90

PMID: 451454


Other references

Frohlich, Hj, 1984: Forest damages and managing browsing wildlife--possibilities and finding solutions. Allgemeine Forstzeitschrift, 39(21): 540-542

Xie, C-H.; Zhao, Z-Y.; Zhou, Y-B.; Gong, F-Q., 2007: Single coronary artery with fistula, right aortic arch, bicuspid aortic valve, and pulmonary stenosis: a rare combination. We report a case of a 10-month-old Chinese girl with single left coronary artery, left coronary artery-to-right ventricle fistula, pulmonary stenosis, and right aorta arch with bicuspid aortic valve. The diagnosis was made by transthoracic echoca...

Sellami, D.; Bouacida, W.; Maalej, A.; Ben Amor, S.; Châabouni, M.; Kamoun, B.; Feki, J., 2008: Retinal neovascularization with myelinated nerve fibers. The prevalence of myelinated retinal nerve fibers is 0.3%-0.6% of eyes. Although they often constitute benign lesions, they are rarely associated with retinal vascular abnormalities including preretinal neovascularization. A 31-year-old patient, w...

Rosenbusch, R.F.; Feng, W., 1996: Coordinate expression of capsular polysaccharide and a membrane-bound capsule-binding protein in Mycoplasma dispar. Abstracts of the General Meeting of the American Society for Microbiology 96(0): 282

Christophe Wersinger; Anita Sidhu, 2009: Partial regulation of serotonin transporter function by -synuclein. Human -synuclein (-Syn) is instrumental in maintaining homeostasis of monoamine neurotransmitters in brain, through its trafficking, and regulation of the cell surface expression and, thereby, activity of dopamine, serotonin and norepinephrine tra...

Giordano, A., 1954: Psychiatric problems in military service. Annali di Medicina Navale 59(4): 376-389

Rehman, AB.; Ahmad, SI., 1981: The effect of warfarin, coumatetralyl and difenacoum on plasma prothrombin time in Tatera indica. Karachi University Journal of Science, 91-2: 55-61

Brandalize, A.Paula.Carneiro.; Schüler-Faccini, Línia.; Hoffmann, J-Sébastien.; Caleffi, M.; Cazaux, C.; Ashton-Prolla, P., 2015: A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study. One of the hallmarks of cancer is the occurrence of high levels of chromosomal rearrangements as a result of inaccurate repair of double-strand breaks (DSB). Germline mutations in BRCA and RAD51 genes, involved in DSB repair, are strongly associat...

Das, A.; Sarin, A.; Saxena, R.K., 2002: Modulation of NK cell activation and interaction with target cells. Natural Killer (NK) cells constitute a class of non-T-non-B lymphocytes, which can spontaneously lyse certain tumor target cells, and therefore may have a role in anti-tumor immune surveillance mechanisms. NK cells constitutively express a low aff...

Kasahara, M.; Kiuchi, T.; Takakura, K.; Uryuhara, K.; Egawa, H.; Asonuma, K.; Uemoto, S.; Inomata, Y.; Ohwada, S.; Morishita, Y.; Tanaka, K., 1999: Postoperative flow cytometry crossmatch in living donor liver transplantation: clinical significance of humoral immunity in acute rejection. Background. The role of humoral immunity in acute rejection in solid organ transplantation remains controversial, although it is known that the presence of antidonor antibodies may precipitate graft rejection. We investigated the clinical relevanc...