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High molecular fibrin derivatives in pre-eclamptic and eclamptic patients

, : High molecular fibrin derivatives in pre-eclamptic and eclamptic patients. European Journal of Obstetrics, Gynecology, and Reproductive Biology 9(2): 105-110

Soluble fibrin monomer complexes were assayed by agarose gel filtration and by ultracentrifugation. Increased values of SFMC were found in the normal third-trimester pregnancies. They were considerably higher in plasma of patients with pre-eclampsia. Concentrations were higher using ultracentrifugation as compared to gel chromatography. Using ultracentrifugation 4 components were identified, indicating that SFMC in this disease are not a homogeneous group.


PMID: 264082

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