geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Influence of pancreatic duct occlusion on islet hormones in peripheral and portal plasma and in the pancreas of the mini-pig


, : Influence of pancreatic duct occlusion on islet hormones in peripheral and portal plasma and in the pancreas of the mini-pig. European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes 17(1): 17-24

In a total of 18 'Göttingen' mini-pigs we studied basal glucose in the peripheral plasma, and the hormones insulin, glucagon, and somatostatin in the peripheral and portal plasma, as well as in extracts of pancreatic tissue, both in animals subjected to pancreatic duct occlusion with prolamine (Occ pigs) 9 months previously and in controls. Additionally, in the pancreas the relative frequency of A-, B-, D- and PP-cells was determined by immunocytochemistry. In peripheral blood of Occ pigs glucose, insulin, and somatostatin were unchanged, while glucagon was decreased. Also after occlusion the portal plasma revealed an increase in insulin but unchanged glucagon and somatostatin, while in the pancreatic tissue insulin and glucagon were statistically unchanged, but somatostatin was reduced. The relative frequency of A-, B-, D- and PP-cells in the pancreatic islets was comparable in both control and Occ pigs. It is concluded that also in the pig pancreatic duct occlusion leads to atrophy of the exocrine pancreas, but leaves undisturbed basal blood glucose, insulin, glucagon and islet cells.

US$29.90

PMID: 2578962


Other references

D.S.lvo, J.; Nelson, S.E.R.; Chien, T.S., 1996: Genistein and L-type Ca-2+ channel antagonists inhibit Ba-2+ entry in A10 vascular smooth muscle cells. Biophysical Journal 70(2 PART 2): A286

Anonymous, 2017: Correction to: Exposure to methyl tert-butyl ether (MTBE) is associated with mitochondrial dysfunction in rat. Xenobiotica; the Fate of Foreign Compounds in Biological Systems 47(5): X-X

Minchin, E., 1965: Varicose veins: some comments and a "new" method of treatment. Medical Journal of Australia 2(22): 918-921

Stone, R.E., 1923: Boot rot and blight of canning Peas. A serious root rot and blight of canning peas occurred during the summer of 1922 in certain parts of Canada. Seed treatment and the application of fertilizers were found to be useless, but it is believed that the disease may be combated to some ex...

Kusumoto, S.; Nagano, M.; Noi, K.; Hashimoto, H.; Neki, M.; Fukuyama, M.; Suetomi, K.; Kobayashi, M.; Okita, I.; Nakanishi, T., 1978: A case of primary pulmonary cryptococcosis--report of a case. Rinsho Hoshasen. Clinical Radiography 23(10): 1053-1056

Fleseriu, M.; Findling, J.W.; Koch, C.A.; Schlaffer, S-Martin.; Buchfelder, M.; Gross, C., 2015: Changes in plasma ACTH levels and corticotroph tumor size in patients with Cushing's disease during long-term treatment with the glucocorticoid receptor antagonist mifepristone. Pituitary effects of long-term therapy with mifepristone, a glucocorticoid receptor antagonist, in Cushing's disease (CD) patients are not well understood. Our objective was to report changes in ACTH and pituitary magnetic resonance imaging (...

Cunningham, I.; Latif, B.M., 1973: The antigenic properties of trypanosomes during their transformation from blood to culture forms. Transactions of the Royal Society of Tropical Medicine and Hygiene 67(2): 270-270

Dabrowski, Z.; Skocze, S.3law, 1962: Paper electrophoresis of the blood serum and haemoglobin of the mole. Mole serum contains 14.6 g. of proteins per 100 ml. These can be separated into 6 fractions. Mole hemoglobin moves to anode in a single band (1.37 x 10-5 cm/v/sec.) Sex, age or season do not influence the electrophoretic properties of serum protei...

Breuer Katschinski, B.; Nemes, K.; Rump, B.; Leiendecker, B.; Marr, A.; Breuer, N.; Goebell, H.; Group, C.P.lyp Study, 1998: Diet and the risk of colonic adenomas. Gastroenterology 114(4 PART 2): A6, April 15

Bonnard, D.; Lautissier, S.; Bosset-Audoit, Aélie.; Coriat, Géraldine.; Beraha, M.; Maunoury, A.; Martel, J.; Darrouzet, V.; Bébéar, J-Pierre.; Dauman, Ré., 2013: Comparison between bilateral cochlear implants and Neurelec Digisonic(®) SP Binaural cochlear implant: speech perception, sound localization and patient self-assessment. An alternative to bilateral cochlear implantation is offered by the Neurelec Digisonic(®) SP Binaural cochlear implant, which allows stimulation of both cochleae within a single device. The purpose of this prospective study was to compare a group...