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Macrophage-mediated cytostasis and lymphocyte cytotoxicity in cattle immunized with Theileria annulata sporozoites or macroschizont-infected cell lines

, : Macrophage-mediated cytostasis and lymphocyte cytotoxicity in cattle immunized with Theileria annulata sporozoites or macroschizont-infected cell lines. Parasite Immunology 10(6): 631-647

Immunization with either sporozoites or macroschizont-infected cell lines protected calves against challenge with lethal doses of sporozoites of Theileria annulata. Stocks from India, Turkey and Morocco all conferred protective immunity to each other, irrespective of the immunizing regime. Although heterogeneous clinical responses were induced by the two immunizing regimes, both stimulated similar patterns of macrophage cytostasis as expressed as an inhibition of proliferation of macroschizont-infected cell lines. Macrophage cytostasis was detected consistently after immunization and after challenge, arising at the same time as macroschizonts were detectable. Its expression was sustained and inhibited the proliferation of both autologous and allogeneic (BoLA-mismatched) cell lines. In contrast, these two immunizing regimes differed in their ability to stimulate the production of cytotoxic cells. Calves immunized with autologous cell lines or sporozoites developed very transient populations of cytotoxic cells expressing only a low level of specific lysis for autologous infected cells; agglutinating antibodies for immunizing or autologous cell lines were not detected in these calves. Calves immunized with allogeneic cell lines produced cytotoxic cells which were specific only for the immunizing cell lines; these calves also produced antibodies which agglutinated the immunizing cell lines.


PMID: 3146048

Other references

Kloiber, J., 1926: Beitrage zur Kaferfauna von Oberosterreichs Verzeichnis der Halticinen oberosterreichs. Jahrbuch der Oberoesterreichischen Musealvereines, 81: 343-360

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Amelung, W.; Stanger, M., 1952: Effect of ultraviolet and infrared rays on autonomic disorders. Munchener Medizinische Wochenschrift 94(11): 502-505

Tse, V.; Wills, E.; Szonyi, G.; Khadra, M., 1999: Ultrastructural basis of detrusor instability and sensory urgency Towards a common mechanism. Journal of Urology 161(4 SUPPL ): 254, April

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Rocha, I.; Albuquerque, S., 1971: On some blattaria of santa catarina brazil dictyoptera. Revta bras Biol, 31: 329-335

Traub, P.; Perides, G.; Kühn, S.; Scherbarth, A., 1987: Efficient interaction of nonpolar lipids with intermediate filaments of the vimentin type. Based on the finding that vimentin isolated and purified from cultured mammalian cells is heavily contaminated by neutral lipids, the binding of a series of radioactively labeled nonpolar lipids to pure, delipidated vimentin was investigated. Empl...

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