+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Mapping of the gene for the cardiac sarcolemmal Na(+)-Ca2+ exchanger to human chromosome 2p21-p23

, : Mapping of the gene for the cardiac sarcolemmal Na(+)-Ca2+ exchanger to human chromosome 2p21-p23. Genomics 12(3): 616-617

The cardiac sarcolemmal Na(+)-Ca2+ exchanger is the primary mechanism for extrusion of calcium from the cardiac myocyte and therefore is important in regulating cardiac contractility. As part of an effort to determine whether the exchanger is associated with any genetic disorders of the heart or blood pressure, we have assigned the exchanger gene (designated NCX1) to human chromosome 2p21-p23 by analysis of a panel of mouse-human somatic cell hybrids and by in situ hybridization.


PMID: 1559714

Other references

Rosenstein, B.J.; Langbaum, T.S., 1980: Incidence of meconium abnormalities in newborn infants with cystic fibrosis. Review of the newborn nursery notes of 87 infants who had cystic fibrosis without meconium ileus (MI) indicated that 12 of them had clinical features consistent with the meconium plug syndrome (MPS). This high incidence of meconium abnormalities s...

Nunthapisud, P.; Sirilertpanrana, S.; Reinprayoon, S.; Tanna, A., 1997: Detection of the erythrogenic toxin A, B, and C genes in group A streptococci isolated from clinical specimens. Advances in Experimental Medicine and Biology 418: 729-731

Annand, J.C., 1962: Osteoarthrosis and Pantothenic Acid. Since the "worn joint" of osteoarthrosis resembles the cartilage and bone lesions produced by acute deficiency of pantothenic acid in rats (Nelson et al., Abst. 367, Vol. 20), a trial was made of treatment with 12.5 mg pantothenic acid t...

Pietrabissa, R.; Reynolds, P., 2016: An Italian Education: IEEE Pulse talks with Riccardo Pietrabissa, president of Italy's National Bioengineering Group, about Italian progress and challenges in biomedical engineering education. From Leonardo da Vinci's designs for ball bearings to the incredible engineering wizardry behind the Ferrari, the inventive, inquisitive, and ingenious spirit of the engineer has always lived--and thrived--in Italy. From education to research...

Saiki, K.; Hirabayashi, S.; Sakai, H.; Inokuchi, K., 2006: Traumatic anterior lumbosacral dislocation caused by hyperextension mechanism in preexisting L5 spondylolysis: a case report and a review of literature. Of many reports referring to injury mechanism in anterior lumbosacral dislocation, there were none concerning hyperextension mechanism. We report a case of a 46-year-old man with preexisting L5 spondylolysis sustaining traumatic complete anterior...

Fuste, F.J.; Ajello, L.; Threlkeld, R.; Henry, J.E., 1973: Drechslera hawaiiensis: causative agent of a fatal fungal meningo-encephalitis. A 31-yr-old- woman died approx. a month after the onset of neurological symptoms including headache, stiffness of the neck, blurring of vision and attacks of generalised shaking. At post-mortem examination unsuspected lymphocytic lymphosarcoma was...

Delattre, C.; Foltran, F.; Bruneau, O.; Thefaut, A-Hélène., 2014: Preventing the risks linked to chewing and swallowing disorders. Various degenerative diseases or pathologies cause chewing and/or swallowing disorders in elderly people as well as in younger patients. In order to prevent the food being swallowed into the airway, a problem which is inherent to these conditions,...

Anderzhanova, E.; Rayevsky, K.S.; Saransaari, P.; Riitamaa, E.; Oja, S.S., 2001: Effects of sydnocarb and D-amphetamine on the extracellular levels of amino acids in the rat caudate-putamen. The neurotoxic effects of psychostimulants at high dosages limit their clinical applicability but the mechanism of neurotoxicity is still unsettled. We now studied by microdialysis how acute and subchronic (four times at 2-h intervals) administrat...

Baker, BR., 1990: The recorder's report for entomology 1989. Reading Naturalist, 42: 31-38

Dolezalova, V., 1961: Damage to the retina caused by solar burn. Ceskoslovenska Oftalmologie 17: 195-197