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Morphological detection of placental anticoagulant protein-I (PAP-I) in human placenta

, : Morphological detection of placental anticoagulant protein-I (PAP-I) in human placenta. Rinsho Byori. Japanese Journal of Clinical Pathology 38(10): 1173-1175

It has been reported that placental anticoagulant protein-I (PAP-I) inhibits the intrinsic and extrinsic pathways of blood coagulation and also the reconstituted prothrombinase activity. However, morphological study on the distribution of PAP-I in whole placenta or in placental cells has not been reported yet. We detected the PAP-I antigen, under light- and electron-microscope, by mean of immuno-cytological techniques. PAP-I was also present in microvilli of the placental syncytiotrophoblast cells and their cortical cytoplasm beneath the villi.


PMID: 2148197

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