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Nitrosobenzene-induced ferrihemoglobin formation in Japanese quail erythrocytes. The significance of ferrihemoglobin reduction


, : Nitrosobenzene-induced ferrihemoglobin formation in Japanese quail erythrocytes. The significance of ferrihemoglobin reduction. Naunyn-Schmiedeberg's Archives of Pharmacology 289(2): 127-135

Quantitative aspects of nitrosobenzene-induced ferrihemoglobin formation were studied in quail erythrocytes in comparison to goat red cells. Many similarities exist with the mechanism in mammalian red cells such as a NADPH-dependent enzymatic recycling of phenylhydroxylamine from nitrosobenzene. Also the mechanism of ferrihemoglobin reduction is similar in both species, it is a NADH-dependent process. However, the reducing activity of quail red cells exceeds by far the activity of the majority of mammalian erythrocytes.

US$29.90

PMID: 1165790


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