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Philadelphia-positive T-acute lymphoblastic leukemia

, : Philadelphia-positive T-acute lymphoblastic leukemia. Cancer Genetics and Cytogenetics 16(4): 297-300

A case of typical T-acute lymphoblastic leukemia (T-ALL) is reported in which, at diagnosis, 100% of bone marrow metaphases showed a Philadelphia (Ph) translocation, t(9;22). These cells completely disappeared following chemotherapy. The significance of the Ph chromosome in T and B leukemic cells is discussed.


PMID: 3872163

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