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Phosphorus-31 magnetic resonance metabolite imaging in the human body

, : Phosphorus-31 magnetic resonance metabolite imaging in the human body. Magnetic Resonance Imaging 10(2): 245-256

This work examines the feasibility of three-dimensional phosphorus-31 magnetic resonance spectroscopic imaging (31P MRSI) of metabolites in the human body using nonselective excitation with a single large circular surface coil for transmitting and receiving. The potential and limitations of this approach to clinical imaging are demonstrated on four selected examples: normal liver and heart, hematoma in the calf, and lymphoma in the groin. The obtained metabolite images showed anatomical detail and allowed differentiation of body organs and pathologic tissue from adjacent tissue. Three-dimensionally localized 31P spectra were reconstructed from nominal volumes of 4 to 15 cm3. These spectra showed characteristic resonances and metabolite intensity ratios for the tissue of origin demonstrating good three-dimensional localization. We conclude that surface coil 31P MRSI of body organs to map metabolite distributions is practically feasible with this approach, but due to experimental limitations, clinical utility requires technical improvements.


PMID: 1564993

Other references

Fayrer-Hosken, R.; Caudle, A., 1990: Canine semen examination with special reference to proximal cytoplasmic droplets and their relation to fertility. Georgia veterinarian 42(5): 11-13

Gerdts, C.; Raifman, S.; Daskilewicz, K.; Momberg, M.; Roberts, S.; Harries, J., 2017: Women's experiences seeking informal sector abortion services in Cape Town, South Africa: a descriptive study. In settings where abortion is legally restricted, or permitted but not widely accessible, women face significant barriers to abortion access, sometimes leading them to seek services outside legal facilities. The advent of medication abortion has f...

Rizescu, M.; Costică, I.; Dornescu, E., 1972: Pure and complicated aortic valve diseases. Medicina Interna 24(3): 305-320

Nilsson-Tillgren, T.; Kielland-Brandt, M.C.; Bekke, B., 1974: Studies on the biosynthesis of tobacco mosaic virus part 6 on the sub cellular localization of double stranded viral rna. Molecular and General Genetics 128(2): 157-169

Melana, E.E., 1988: Barnacle infestation in mangroves. A note on barnacle (Balanus spp.) infestation in Philippine mangroves, including suggested silvicultural methods for minimizing its occurrence.

Maubert, E.; Dupouy, J.P.ul; Bernet, F., 1993: Effect of adrenal demedullation on neuropeptide Y content of the capsule/glomerulosa zone of the rat adrenal gland. 154 capsule/glomerulosa zone of the adrenal gland is richly innervated by neuropeptide Y (NPY)-containing nerve fibers. The content and concentration of NPY in the capsule/glomerulosa zone of the female rat adrenal were determined by radioimmunoas...

Rubin, S.; Leclerc, S., 2001: A practical guide to recognizing and treating hypokalemia. Veterinary medicine 96(6): 462-476not

Hinz, S.; Weikert, S.; Magheli, A.; Hoffmann, Mèle.; Engers, R.; Miller, K.; Kempkensteffen, C., 2009: Expression profile of the polycomb group protein enhancer of Zeste homologue 2 and its prognostic relevance in renal cell carcinoma. EZH2 increases the proliferation rate and apoptosis resistance of renal cell carcinoma cell lines. To date its clinical impact on the outcome in patients with renal cell carcinoma is not known. To our knowledge this is the first study of the assoc...

Chantawibul, S.; Lokechareonlarp, S.; Pokawatana, C., 2003: Total video endoscopic thyroidectomy by an axillary approach. A permanent transverse surgical scar is an unavoidable problem after conventional thyroidectomy. Endoscopic thyroidectomy performed via an axillary approach leaves no scarring at the neck and anterior chest wall and so provides an excellent cosmet...

Murray, A.; Brashear, D., 1992: Older patients--specialized care. Nursing 22(9): 88-88