geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Prevention of recurrent urinary tract infections in premenopausal women by post-coital administration of cinoxacin


, : Prevention of recurrent urinary tract infections in premenopausal women by post-coital administration of cinoxacin. Journal of Urology 139(6): 1250-1252

A total of 21 sexually active premenopausal women, prone to recurrent urinary tract infections but who otherwise were healthy, underwent post-coital prophylaxis consisting of bladder voiding and a single 250 mg. tablet of cinoxacin. While 94 urinary tract infections occurred during a mean of 7.5 months before treatment, only 8 occurred during a mean of 12.5 months after prophylaxis. This difference was statistically highly significant. A mean of 106 cinoxacin tablets per patient were administered during post-coital prophylaxis. Cinoxacin represents an additional valuable and effective antibacterial in post-coital prophylaxis of recurrent urinary tract infection in otherwise healthy premenopausal women, although it is slightly less effective than cotrimoxazole or nitrofurantoin. Effective post-coital prophylaxis requires the use of much smaller quantities of antibacterial agents than the daily use of a single tablet and in women with a high incidence of recurrent urinary tract infections it is superior to intermittent self-administered antibacterial therapy.

US$29.90

PMID: 3286892


Other references

Ponnala, S.; Chaudhary, S.; González-Sarrias, A.; Seeram, N.P.; Harding, W.W., 2011: Cytotoxicity of aporphines in human colon cancer cell lines HCT-116 and Caco-2: an SAR study. A series of synthetic aporphine derivatives structurally related to domesticine and nantenine (ring A, N6 and ring C truncated analogs), was evaluated in MTS cytotoxicity assays against the human colon cancer cell lines, HCT-116 and Caco-2. In gen...

Rusby J.S.M.; Revie J., 1975: Long-range sonar mapping of the continental shelf. Recent experiments in the shallow waters of the continental shelf off the west coast of Scotland have shown that it is possible to obtain geologically useful sonographs from a towed low-frequency side-scan sonar (GLORIA project) out to long ranges...

Kaas, J.; Hall, W.C.; Diamond, I.T., 1970: Cortical visual areas I and II in the hedgehog: relation between evoked potential maps and architectonic subdivisions. Journal of Neurophysiology 33(5): 595-615

Stanisławska-Sachadyn, A.; Woodside, J.V.; Brown, K.S.; Young, I.S.; Murray, L.; McNulty, H.; Strain, J.J.; Boreham, C.A.; Scott, J.M.; Whitehead, A.S.; Mitchell, L.E., 2008: Evidence for sex differences in the determinants of homocysteine concentrations. A high homocysteine phenotype, often accompanied by low folate, is associated with several pathologies including cardiovascular disease and birth defects. This phenotype appears to be influenced by both genetic and environmental factors, which may...

W.A.drew Jackson; Alfonso F.D.vila; Nubia Estrada; W.B.rry Lyons; John D.C.ates; John C.P.iscu, 2012: Perchlorate and chlorate biogeochemistry in ice-covered lakes of the McMurdo Dry Valleys, Antarctica. We measured chlorate (ClO<inf loc="post">3</inf> <sup loc="post">-</sup>) and perchlorate (ClO<inf loc="post">4</inf> <sup loc="post">-</sup>) concentrations i...

Sun, X.; Si, L.; Cao, Z.; Wang, Y.; Liu, T.; Guo, J., 2002: Immune response to plasmid DNA encoding HPV16-L1 protein. Chinese Medical Journal 113(3): 277-280

Goedhart, G.; van Eijsden, M.; van der Wal, M.F.; Bonsel, G.J., 2008: Ethnic differences in preterm birth and its subtypes: the effect of a cumulative risk profile. To explore the effect of potentially explanatory risk factors on ethnic differences in the prevalence of preterm birth (PTB) and its subtypes. Prospective population-based cohort study. Pregnant women from Amsterdam attending their first antenatal...

Marciński, A., 1976: The role of arteriography in the diagnosis of abdominal tumours in children. Polski Przeglad Radiologii i Medycyny Nuklearnej 40(2): 117-125

Heintz, B.H.; Halilovic, J.; Christensen, C.L., 2011: Vancomycin-resistant enterococcal urinary tract infections. Enterococci are a common cause of urinary tract infections (UTIs) among hospitalized patients. The rising prevalence of vancomycin-resistant enterococci (VRE) is of particular concern within many institutions because of its association with increa...

Abboud, H.E.; Dousa, T.P., 1983: Action of adenosine on cyclic 3',5'-nucleotides in glomeruli. Recent in vivo studies indicated that adenosine has a profound effect on glomerular dynamics and renal circulation. Because its effect in nonrenal tissues is frequently mediated by adenosine 3',5'-cyclic monophosphate (cAMP), we examined...