geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Restoring sensitivity to timolol after long-term drift in primary open-angle glaucoma


, : Restoring sensitivity to timolol after long-term drift in primary open-angle glaucoma. Investigative Ophthalmology & Visual Science 31(2): 354-358

In a prospective randomized single-masked study lasting 6 months, 39 eyes with primary open-angle glaucoma showing a long-term drift with 0.5% timolol were put on a "timolol holiday" lasting 30 or 60 days. Twenty-three of them were enrolled with dipivefrin 0.1% twice daily during the holiday. When timolol therapy was restored, the dipivefrin-treated group showed a more pronounced decrease of intraocular pressure (IOP) (8.2 +/- 1.5), whereas the IOP decrease in the nondipivefrin-treated group was lower (3.9 +/- 1.2) and of shorter duration (less than 60 days). Among the dipivefrin-treated group, the response to timolol was more prolonged in the eyes treated for 60 days: the IOP of these eyes was less than 23 mmHg throughout the follow-up.

US$29.90

PMID: 2406218


Other references

Stevenson, D.; El-Sharif, H.F.; Reddy, S.M., 2016: Selective extraction of proteins and other macromolecules from biological samples using molecular imprinted polymers. NlmCategory="UNASSIGNED">The accurate determination of intact macromolecules in biological samples, such as blood, plasma, serum, urine, tissue and feces is a challenging problem. The increased interest in macromolecules both as candi...

Ramaiah, K.V., 1987: Breeding cereal grains for resistance to witchweed. Work on breeding for witchweed (Striga) resistance in sorghum, millet [Pennisetum americanum?] and maize is reviewed with particular emphasis on sorghum. Also discussed are variability in Striga species in relation to breeding for broad-spectrum s...

Magee Brian R.; Schuyler Steven E.; Kufs Charles, 1990: The use of background concentrations in site assessments. Ground Water Management 1: 861-876

Tsunematsu, Y.; Fukui, H.N.; Kinoshita, J.H., 1978: Studies on primary cultures of adult lens cells from normal and hereditary cataractous mice. Lens epithelial cells from normal and congenital cataractous mice strains were cultured under similar conditions. Normal and cataractous cells actively propagated and reached confluency on the 11th day. Thereafter, these cells underwent morphologi...

Killgore, W.D.S.; Yurgelun-Todd, D.A., 2007: Neural correlates of emotional intelligence in adolescent children. The somatic marker hypothesis posits a key role for the ventromedial.prefrontal cortex, amygdala, and insula in the ability to utilize emotions to guide decision making and behavior. However, the relationship between activity in these brain regio...

Montanari, G.; Fornasiero, S.; Magri, C.; Palmieri, F.; Giacalone, E.; Iacomino, R.; Bertozzi, P.; Trogolo, P.; Saggiorato, V., 1993: Reception of the patient in intensive care. Minerva Anestesiologica 59(11): 589-595

Iacono J.M.; Zellner D.C.; Paoletti R.; Ishikawa T.; Frigeni V.; Fumagalli R., 1974: Comparison of blood platelet and erythrocyte lipids in man in 3 age groups from 3 regions milan cincinnati and sicily. Haemostasis 2(1-4): 141-162, 1973

Kirchgatterer, A.; Wenzl, H.H.; Aschl, G.; Hinterreiter, M.; Stadler, B.; Hinterleitner, T.A.; Petritsch, W.; Knoflach, P., 2002: Examination, prevention and treatment of osteoporosis in patients with inflammatory bowel disease: Recommendations and reality. Background: Patients with inflammatory bowel disease (IBD) are at increased risk of developing osteopenia and osteoporosis. Our aim was to evaluate the current practices of examination, prevention and treatment of osteoporosis in IBD patients in a...

Masuda, T.; Hidaka, K.; Shinohara, A.; Maekawa, T.; Takeda, Y.; Yamaguchi, H., 1999: Chemical studies on antioxidant mechanism of curcuminoid: analysis of radical reaction products from curcumin. In the course of studies on the antioxidant mechanism of curcumin, its radical reaction was investigated. Curcumin was reacted with radical species, which were generated from the pyrolysis of 2,2'-azobis (isobutyronitrile) under an oxygen atm...

Oktiabr'skiĭ, O.N.; Ushakov, V.Iu.; Muzyka, N.G.; Smirnova, G.V., 2009: The role of thiol redox systems in response of Escherichia coli to distant UV irradiation. Mikrobiologiia 78(3): 328-333