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Role of microcirculation in the development of pulmonary hypertension in chronic non-specific lung diseases

, : Role of microcirculation in the development of pulmonary hypertension in chronic non-specific lung diseases. Kardiologiia 16(11): 18-23

A comparison of the results of morphological studies of pulmonary and pleural microcirculation with the indices of haemodynamics in the system of the pulmonary artery in patients with chronic non-specific lesions of the lungs accompanied by suppurative processes indicates the participation of microcirculation in the development of pulmonary hypertension. A lasting course of the disease with frequent exacerbations results in profound changes in the system of micricirculation. The pathological developments in the vascular terminals, the disorders in the rheological properties of the blood, in vascular permeability- the hampered lymph drainage that are the causes of irreversible metabolic shifts not only become additional factors in the development of the underlying pathology, in the formation of bronchiectases in particular, but also provide for a further development of pulmonary hypertension.


PMID: 1011461

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