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Solubility and partitioning. IX: Solubility of hydantoins in water


, : Solubility and partitioning. IX: Solubility of hydantoins in water. Journal of Pharmaceutical Sciences 77(6): 518-522

An expression for estimating the aqueous solubility of weak electrolytes under different conditions of temperature and pH has been proposed in a previous publication. The expression, based on the additivity of free energy, separates solubility into three independent contributions. In the present work, the equation is tested with a different set of 18 solutes within the range of temperature of 20 to 50 degrees C and of pH of 1 to 10. The results show that the theoretical relationship between aqueous solubility and the three independent contributions used in the equation is in excellent agreement with the experimental data.

US$29.90

PMID: 3171932


Other references

FitzGerald, M.X.; Carrington, C.B.; Gaensler, E.A., 1973: Environmental lung disease. Medical Clinics of North America 57(3): 593-622

Novelli, G.; Borgiani, P.; Ciccacci, C.; D.D.niele, N.; Sirugo, G.; Papaluca Amati, M., 2010: Pharmacogenomics: role in medicines approval and clinical use. Pharmacogenomics (PGx) and pharmacogenetics (PGt) are emerging interdisciplinary areas recently defined by the regulatory authorities at an international level as 'the investigation of variations of DNA and RNA characteristics as related to d...

Anonymous, 2016: Reply by Hueber et al. Journal of Urology 195(1): 229-230

Trentz O.; Sutter G., 1988: Posttraumatic respiratory failure. Atemwegs-und Lungenkrankheiten 14(12): 578-581

Bardyshev, I.I.; Bulgakov, A.N.; Udarov, B.G.; Zimina, N.G., 1979: Chemical composition of the oleoresin produced by individual trees of Pinus sylvestris subspp. sylvestris and sibirica. In a study of the quantitative composition of monoterpenoid hydrocarbons (turpentines) and resin acids in trees of P. sylvestris (Belorussian type) and P. sibirica (Enisei type), the turpentines of individual trees of both species differed appreci...

Foeldes Papp, Z.; Baumann, G.; Birch Hirschfeld, E.; Eickhoff, H.; Greulich, K.O.to; Kleinschmidt, A.K.; Seliger, H., 1998: The Analysis of oligonucleotide preparations by fractal measures. In this paper we put forward improved mathematical methods for detecting synthesis parameters in connection with analyzing crude products of chemically synthesized oligonucleotides. The crude products experimentally sampled are separated by high-p...

Liberato, D.J.; Saavedra, J.E.; Farnsworth, D.W.; Lijinsky, W., 1989: Thermospray liquid chromatography/mass spectrometry studies on mechanisms of nucleic acid alkylation by some deuterated carcinogens. Alkylation of liver nucleic acids of rats treated with nitrosobis(2-oxopropyl)amine (BOP), nitrosomethyl(2-oxopropyl)amine (NMOP), and (methylazoxy)methane (AOM) was studied by using deuterium-labeled compounds. Six hours after treatment of each r...

Lechertier, T.; Berard, M.; Vassy, R.; Herve, M.A.; Crepin, M., 2005: Transendothelial migration of two metastatic breast carcinoma cells depend on the SDF-lalpha-CXCR4 complexes. The role of the SDF-1alpha chemokine-CXCR4 receptor system on tumor cell transendothelial migration was studied by culturing metastatic breast tumor cell lines, MDA-MB-231 and MDA-MB-435, either alone or on a HUVEC monolayer pre-established on a &...

Mclean, W.H.I.; Morley, S.M.; Eday, R.A.J.; Dopping Heppenstal, P.J.C.; Mcmillan, J.R.; Leigh, I.M.; Navsaria, H.A.; Higgins, C.; Harper, J.I.; Paige, D.G.; Lane, B., 1993: Bullous congenital ichthyosiform erythroderma of BROCQ caused by both disruptive and highly conservative amino acid substitutions in the 1A domain of keratins 1 and 10. Journal of Investigative Dermatology 101(3): 404

Jones, C.A.; McArdle, A.H.; Hinchey, E.J., 1977: The enhancement of adenyl cyclase by steroid therapy in shock. Hepatic and intestinal adenyl cyclase activity were measured after a single pulse injection of epinephrine or glucagon into normal dogs and into dogs subjected to hemorrhagic shock. The results indicated that hemorrhagic shock abolishes the increa...