geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Structural and transcriptional properties of different nucleosomal particles containing high mobility group proteins 14 and 17 (HMG 14/17)


, : Structural and transcriptional properties of different nucleosomal particles containing high mobility group proteins 14 and 17 (HMG 14/17). Journal of Biological Chemistry 265(14): 8225-8229

Binding of high mobility group (HMG) proteins 14 and 17 (HMG 14/17) to complete nucleosomal cores and to cores lacking one H2A.H2B dimer, the amino-terminal tails of histones, or both one H2A.H2B dimer and the amino-terminal ends of histones is accompanied by an overall stabilization of the particles as determined by thermal denaturation, circular dichroism and DNase I digestion. In spite of the structural stabilization brought about by HMG 14/17, the presence of these proteins causes little effect on the efficiency of the different nucleosomal particles as transcription templates for RNA polymerase II. The nucleosomal particles lacking one H2A.H2B dimer and containing two bound HMG 14/17 molecules are efficient in vitro transcription templates, which allow transcription of the whole length of the DNA present in the particle. These results are consistent with HMG 14/17 being present in active chromatin.

US$29.90

PMID: 1692325


Other references

Goff, J.; Dominey-Howes, D.; Chague-Goff, C.; Courtney, C., 2010: Analysis of the Mahuika comet impact tsunami hypothesis. A comet impact on February 13, 1491 AD, 250 km SW of New Zealand, named "Mahuika", has been proposed as the tsunamigenic source for an alleged large 15th century tsunami along the New Zealand and east Australian coastlines. This hypothes...

Anonymous, 1978: ILO: working and living conditions of nursing personnel - convention and recommendations. Zeitschrift für Krankenpflege. Revue Suisse des Infirmieres 71(5): 198-9, 207-11

Carvalho, R.; Kurochka, S.; Rocha, J.; Fernandes, Jão.Soares., 2012: Brown tumor of the mandible: Magnetic susceptibility demonstrated by MRI. We present a case of a 75-year-old woman with right mandible cystic lesion and primary hyperparathyroidism. The MRI demonstrated marked loss of signal intensity on T2 gradient-echo images, suggesting intralesional hemossiderin. After an open biops...

Chaignon, V.; Lartiges, B.S.; E.S.mrani, A.; Mustin, C., 2002: Evolution of size distribution and transfer of mineral particles between flocs in activated sludges: An insight into floc exchange dynamics. The aggregation behavior of activated sludge flocs was investigated by monitoring the size distribution of flocs and transfer of mineral particles between flocs, under various conditions of agitation and dilution. The results showed that (i) the s...

Maher, H.M.; Youssef, R.M.; Hassan, E.M.; El-Kimary, E.I.; Barary, M.A., 2011: Enhanced spectrophotometric determination of two antihyperlipidemic mixtures containing ezetimibe in pharmaceutical preparations. Two spectrophotometric methods are presented for the simultaneous determination of ezetimibe/simvastatin and ezetimibe/atorvastatin binary mixtures in combined pharmaceutical dosage forms without prior separation. The first is the derivative ratio...

Simon, E.R., 1991: Identification of recipients with hepatitis C and other transfusion-transmitted infections: we can do better than look-back!. Transfusion 31(1): 87-87

Sansgiry, S.S.; Shringarpure, G.S., 2003: Springtime confusion: are consumers getting the right information on how to treat seasonal allergies?. Journal of Allergy and Clinical Immunology 112(3): 627-628

Fillion, L.; de Serres, M.; Lapointe-Goupil, R.; Bairati, I.; Gagnon, P.; Deschamps, Mèle.; Savard, Jée.; Meyer, Fçois.; Bélanger, L.; Demers, G., 2006: Implementing the role of patient-navigator nurse at a university hospital centre. A profile of the role and functions of an oncology patient-navigator nurse (OPN) and the preliminary phases to implementing this role within a team specializing in oncology are first presented. This is followed by a qualitative study that provides...

Shen, M.; Gao, J.; Li, J.; Su, J., 2009: Effect of stimulation frequency on angiogenesis and gene expression in ischemic skeletal muscle of rabbit. To examine the comparative effects of different frequencies of electrical stimulation (ES) on angiogenesis and gene expression, New Zealand white rabbits with femoral artery ligation in one hindlimb and electrode implantation on the sciatic nerve...

Fisher, M.; Nagarkatti, P.S.; Nagarkatti, M., 2003: TCDD-induced loss of mitochondrial membrane potential in spermatozoa is independent of Fas AND FasL. Toxicological Sciences 72(S-1): 66, March