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Studies on WB-3559 A, B, C and D, new potent fibrinolytic agents. I. Discovery, identification, isolation and characterization

, : Studies on WB-3559 A, B, C and D, new potent fibrinolytic agents. I. Discovery, identification, isolation and characterization. Journal of Antibiotics 38(11): 1469-1475

WB-3559 A, B, C and D were produced by a bacterium which was classified as a member of the genus Flavobacterium. These compounds were purified by solvent extraction followed by chromatography on silica gel and then isolated by HPLC. The chemical structures were determined on the basis of chemical and spectroscopic evidence as in the succeeding papers. WB-3559 A, B, C and D stimulated rabbit plasma euglobulin clot lysis time. A chemically synthesized compound (WB-3559 D-syn) stimulated mouse plasma euglobulin clot lysis time when injected intravenously.


PMID: 4077726

Other references

Gasiewicz T.A.; Rucci G., 1984: Uptake and properties of receptors for 2 3 7 8 tetra chloro di benzo p dioxin in hepatic nuclei from various mammalian species. Federation Proceedings 43(3): ABSTRACT 2380

Turkaslan, S.; Baykul, T.; Aydin, M.Asim.; Ozarslan, M.Mustafa., 2009: Articulation performance of patients wearing obturators with different buccal extension designs. The primary goal of prosthetic obturation is closure of the maxillectomy defect and separation of the oral cavity from the sinonasal cavities by use of different bulb designs. The aim of this study was to evaluate the articulation performance of o...

Bruns N.J.; Webb K.E.Jr, 1988: Humoral and cell mediated immunity in vitamin a deficient lambs. Journal of Animal Science 66(SUPPL 1): 30-31

Herrmann, H., 1960: Direct metabolic interactions between animal cells. Science New York, 132: 529-532

Mazaro, Jé.Vitor.Quinelli.; da Silva, C.Ramos.; Filho, H.Gennari.; Zavanelli, A.Cristina.; de Mello, C.Cantieri.; Lemos, C.Aparecido.Araujo.; Pellizzer, E.Piza., 2016: Stress Analysis of Axial and Tilted Implants in Full-arch Fixed Dentures Under Different Abutment Conditions. The aim of this study was to evaluate the stress distribution on full-arch prostheses, considering axial implants and tilted implants with or without abutments. Two photoelastic models were made, being that in 1 model the implants were inserted pe...

Setchell, D.J., 1972: Functionally generated paths in occlusal surface design. Apex 6(4): 149-151

S.John, R., 1969: Schizophrenic blocking and the blank dream. Psychoanalytic Quarterly 38(2): 275-286

Foote, W.E.; Sheard, M.H.; Aghajanian, G.K., 1969: Comparison of effects of LSD and amphetamine on midbrain raphe units. Nature 222(5193): 567-569

Lien Y H.H., 1992: Differential regulation of organic osmolytes in brain cells cultured in isotonic and hypertonic media. Clinical Research 40(1): 112A

Bychkov, V.A.; Sakharova, A.E.; Rodionova, S.N., 1976: Clinical picture and treatment of acute purulent destruction of the lungs in children. Meditsinskaia Sestra 35(10): 15-18