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Study of mastocytes in 1298 bone biopsies. Relationship between mastocytes and osteoporosis

, : Study of mastocytes in 1298 bone biopsies. Relationship between mastocytes and osteoporosis. Revue du Rhumatisme et des Maladies Osteo-Articulaires 58(11): 759-761

The relationship between the bone damage in systemic mastocytosis and reactional mastocytosis is still poorly understood. The purpose of this study was to determine the incidence of excessive mastocytes in a series of bone biopsies and their significance in cases of osteoporosis. The mastocytes were routinely counted in 1,298 successive biopsies stained with May Grumwald Giemsa: 131 biopsies had more than 5 mastocytes/mm2, i.e., 10% of all samples for all diagnoses combined. In 11 patients (13 bone biopsies) with a large excess of mastocytes (more than 15/mm2) and osteoporosis, the biopsies were examined again to look for mastocytic nodules suggesting bone mastocytosis: mastocytic nodules of this type were found in only 4 cases. The mastocyte is an active cell which may play a role in bone metabolism through the intermediary of its mediators. In osteoporosis, the incidence and significance of excessive mastocytes is not yet understood; this excess of mastocytes appears to correspond to reactive mastocytosis rather than systemic mastocytosis.


PMID: 1780650

Other references

Caola, G.F.rlazzo, A.O.ero, A., 1975: Serum glycoproteins and type of transport in the pig. Atti ub 1975), 28 371-377

Margolis, L.; Arai, H.P., 1989: Synopsis of the parasites of vertebrates of Canada: parasites of marine mammals. This synopsis contains parasite-host and host-parasite lists for 74 species of parasites from 26 species (1 with 2 subspecies) of marine mammals from Canadian waters. The 74 species are distributed among higher taxa as follows: Protozoa - 2; Trema...

Dame, W.R.; Quackernack, K., 1977: A new needle for low risk amniocentesis in early pregnancy. A new needle will be described, which has been especially useful for amniocentesis in early pregnancy. Construction is based on the principle of the Verres-needle. After passing through the abdominal wall and entering the amniotic sac, a blunt sty...

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Lennartz, H., 1953: Cardiovascular symptoms and convulsive attacks in tic douloureux of the glossopharyngeal nerve. Der Nervenarzt 24(11): 470-472

McCoy, K., 1992: A generation gap?. Insight 17(4): 3-3

Verlaan, J.J.; Dhert, W.J.A.; Oner, F.C., 2005: Vertebroplasty for burst fractures. Journal of Neurosurgery. Spine 2(3): 398-9; Author Reply 399

Wenger, T.; Tramu, G.; Leonardelli, J., 1986: Enkephalin-like immunoreactivity in the adult rats corpus luteum. Methionine-enkephalin (M-enk) and leucine-enkephalin (L-enk) were detected by PAP immunohistochemical method in the corpus luteum but not in the follicles of the rat ovary.

Singh, A., 1984: Studies on gestation period in Murrah buffaloes. 902 gestation records on 269 buffaloes at 2 farms during 1959-78 were analysed. Overall, gestation length averaged 303.12+or-1.31 days (CV = 3.82%). Farm, season, parity and sex of calf had no significant effect on gestation length, whereas period...

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