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The production of 99mTc-labeled conjugated antibodies using a cyclam-based bifunctional chelating agent


, : The production of 99mTc-labeled conjugated antibodies using a cyclam-based bifunctional chelating agent. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology 14(6): 569-572

A bifunctional chelating agent (BFCA) based on a macrocyclic amine, cyclam, was used to form specifically 99mTc labeled rabbit-anti-HSA-antibodies. This study demonstrates the feasibility of forming a highly stable cyclam-based 99mTc-BFCA with its subsequent conjugation to antibodies.

US$29.90

PMID: 3429238


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