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The role of albumin in human physiology and pathophysiology, Part III: Albumin and disease states


, : The role of albumin in human physiology and pathophysiology, Part III: Albumin and disease states. Jpen. Journal of Parenteral and Enteral Nutrition 15(4): 476-483

The serum albumin level is one of several clinical parameters of the status of general health. There is a marked correlation between low albumin levels and the incidence of morbidity and mortality in hospitalized patients. Therefore, it is not surprising to find that hypoalbuminemia is a common finding among hospitalized patients. This results from alterations in the catabolic or anabolic rates, losses of albumin, or redistribution between the various fluid compartments of the body. Somewhat less well defined than the role of albumin as a prognostic indicator is its role in compounding pathophysiology. Hypoalbuminemia is known to be associated with delayed wound healing. The hypoalbuminemic state interferes with the normal functioning of the gastrointestinal tract. Qualitative changes in the albumin molecule which occur in renal disease may damage the nephron. Low serum albumin levels may adversely affect the coagulation system. Further investigation into the role of albumin in pathophysiology is warranted.

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PMID: 1895489


Other references

Thomaz, P.Marcondelli.Dias.; Silva, E.Freitas.da.; Costa, T.Helena.Macedo.da., 2014: Validity of self-reported height, weight and body mass index in the adult population of Brasilia, Brazil. To assess the validity of self-reported weight, height and body mass index (BMI) estimates from adults in Brasilia and to identify factors associated to differences between measured and self-reported values. In a cluster sampling 250 households we...

Bourgeois, P.; Benoist, M.; Palazzo, E.; Belmatoug, N.; Folinais, D.; Frot, B.; Busson, G.; Lassale, P.; Montagner, C.; Binoche, T., 1988: Multicenter randomized double-blind study of triamcinolone hexacetonide versus chymopapain in the treatment of disk lumbosciatica. Initial results at 6 months. Revue du Rhumatisme et des Maladies Osteo-Articulaires 55(10): 767-769

Urasa, I.T.; Macha, S.F., 1999: Investigation into heavy metal uptake by waste water sludges. Preliminary laboratory studies with composted sludge have shown that this material has a high affinity for metals. This metal uptake property appears to be particularly pronounced for lead, for which the material showed a retention capacity of 15%...

Zhu, H.; Jiang, X-Xia.; Wu, Y.; Liu, Y-Lin.; Li, X-Sen.; Zhang, Y.; Mao, N., 2011: Identification of mesenchymal stem cells derived from rheumatoid arthritis synovial fluid and their regulatory effect on osteoblast formation. This study was purposed to investigate the influence of inflammatory microenvironment on mesenchymal stem cells (MSCs) and regulatory effect of MSCs on osteoblast formation. The MSCs were isolated from synovial fluid of patients with rheumatoid ar...

Hadid, C.; D.T.ro, D.; Gallino, S.; Labadet, C., 2012: Antegrade or retrograde accessory pathway conduction: who dies first?. A 36 year-old man with Wolff Parkinson White syndrome due to a left-sided accessory pathway (AP) was referred for catheter ablation. Whether abolition of antegrade and retrograde AP conduction during ablation therapy occurs simultaneously, is uncl...

Denoth, M.; Myers, J.H., 2007: Competition between Lythrum salicaria and a rare species: combining evidence from experiments and long-term monitoring. The rare endemic plant Sidalcea hendersonii (Henderson's checker-mallow) occurs in tidal marshes of the Pacific Northwest and may be threatened by Lythrum salicaria (purple loosestrife), a European invader plant. We compared the abundances o...

Bulow, V.; Rudolph, R.F.chs, B., 1986: Enhanced pathogenicity of chicken anaemia agent (CAA) in dual infections with Mareks disease virus (MDV), and infectious bursal disease virus (IBDV) or reticuloendotheliosis virus (REV). Journal of veterinary medicine: Series B = Zentralblatt fur Veterinarmedizin: Reihe B 33(2): 93-116

Davis, C.; Fischer, J.; Ley, K.; Sarembock, I.J., 2003: The role of inflammation in vascular injury and repair. Inflammation plays a critical role in the vascular response to injury. In particular, mechanical injury using techniques such as balloon angioplasty and stenting results in complex inflammatory reactions which influence proliferation of vessel wal...

Bennett A.; Collins P.O.; Melhuish P.B.; Peacock L.E.; Stamford I.F.; Tavares I.A., 1985: Drugs affecting eicosanoids in gastric mucosa and gastrointestinal muscle. Digestive Diseases & Sciences 30(4): 369

Oshima, N.; Makino, M.; Iwamuro, S.; Bern, H.A., 1996: Pigment dispersion by prolactin in cultured xanthophores and erythrophores of some fish species. The direct effects of a pair of tilapia prolactins (tPRL-177 and tPRL-188) and of ovine prolactin (oPRL) on cultured xanthophores and erythrophores isolated from some fish species were examined. Cultured xanthophores of the Nile tilapia, paradise...