geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Thermotolerance and the heat-shock response in Candida albicans


, : Thermotolerance and the heat-shock response in Candida albicans. Journal of General Microbiology 135(9): 2509-2518

At elevated temperatures, yeast cells of Candida albicans synthesized nine heat-shock proteins (HSPs) with apparent molecular masses of 98, 85, 81, 76, 72, 54, 34, 26 and 18 kDa. The optimum temperature for the heat-shock response was 45 degrees C although HSPs were detected throughout the range 41-46 degrees C. Protein synthesis was not observed in cells kept at 48 degrees C. Yeast cells survived exposure to an otherwise lethal temperature of 55 degrees C when they had previously been exposed to 45 degrees C. The thermotolerance induced during incubation at 45 degrees C required protein synthesis, since protection was markedly reduced by trichodermin. Mercury ions induced a set of three stress proteins, one of which corresponded in size to an HSP, and cadmium ions evoked one stress protein seemingly unrelated to the HSPs observed after temperature shift.

US$19.90

PMID: 2697750

DOI: 10.1099/00221287-135-9-2509


Other references

Markham J.W., 1968: Studies on the haptera of laminaria sinclairii. Syesis 1(1-2): 125-131

Kim, P.K.; Janiak-Spens, F.; Trimble, W.S.; Leber, B.; Andrews, D.W., 1997: Evidence for multiple mechanisms for membrane binding and integration via carboxyl-terminal insertion sequences. Subcellular localization of proteins with carboxyl-terminal insertion sequences requires the molecule be both targeted to and integrated into the correct membrane. The mechanism of membrane integration of cytochrome b-5 has been shown to be promis...

Yalcin, S.; Akyurt, I.; Solak, K., 2001: Stomach contents of the catfish (Clarias gariepinus Burchell, 1822) in the River Asi (Turkey). Natural food items of catfish (Clarias gariepinus Burchell, 1822) were investigated in the River Asi from September 1996 to October 1998. Analyses of stomach contents showed that the catfish feed basically on Arthropoda, mostly Diptera larvae, and...

Cameron R.J., 1970: Translocation of carbon 14 labelled assimilates in shoots of pinus radiata g the effects of girdling and indolebutyric acid. Journal of Experimental Botany 21(69): 943-950

Cinatl, J.; Cinatl, J.; Scholz, M.; Driever, P.H.; Henrich, D.; Kabickova, H.; Vogel, J.U.; Doerr, H.W.; Kornhuber, B., 1996: Antitumor activity of sodium valproate in cultures of human neuroblastoma cells. Valproic acid (VPA) is a simple branched-chain fatty acid that has anticonvulsant activity and is widely used in the treatment of epilepsy. VPA was found to effect growth and differentiation of human neuroblastoma (NB) cells in vitro at concentrat...

Brown, A., 1981: The road to despair. Nursing Mirror 153(9): 8-9

Farzana, M.Hasmath.; Meenakshi, S., 2015: Exploitation of zinc oxide impregnated chitosan beads for the photocatalytic decolorization of an azo dye. Investigations were made to evaluate and distinguish the photocatalytic decolorization of Reactive Red 2 (RR) dye using zinc oxide (ZnO) and zinc oxide impregnated chitosan beads (ZCB) under UV and visible light irradiations. To enhance the photor...

Flood, A.; Lacey, J.V.Jr; Schairer, C.; Schatzkin, A., 2001: Meat consumption and risk of colorectal cancer in a prospective cohort of women. Proceedings of the American Association for Cancer Research Annual Meeting 42: 765-766, March

Sturhan, D., 1960: Einge bemerkenswerte Vorkommen des Stengelalchens, Ditylenchus dipsaci (Kuhn), in Bayern. Sturhan gives details and describes symptoms shown by various plants attacked by stem eelworm, Ditylenchus dipsaci, in Bayern. New records include D. dipsaci on Digitalis grandiflora, D. parviflora, Hibiscus sp. and Colchicum autumnale. There was...

Yao, J.J.; Cheng, Z.; Ce, C.C.; Hai, W.C.; Xiang, Z.Y.; Cheng, L.B., 1988: Beta-endorphin-like immunoreactivity increases in cerebrospinal fluid of acute head-injured patients. beta-endorphin-like immunoreactivity (beta-ELI) was measured in cerebrospinal fluid (CSF) of 36 acute head-injured patients and 12 patients without head injury as controls. The mean level of beta-ELI in CSF of controls, mild cerebral contusions, a...