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Total lymphoid irradiation


, : Total lymphoid irradiation. Rheumatic Diseases Clinics of North America 15(3): 577-582

Total lymphoid irradiation (TLI) was shown to have potent immunosuppressive effects in patients with Hodgkin's disease. In the last decade a handful of studies assessed the efficacy of TLI in patients with rheumatoid arthritis. A correlation between decline in T-helper cell number and a reduction in disease activity was noted in all studies; however, the toxicity of TLI remains a major problems limiting a more widespread use of this treatment modality.

US$29.90

PMID: 2672139


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