+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Triphasic reduction of bH and the absence of equilibration at the i-site of bc1 complex

, : Triphasic reduction of bH and the absence of equilibration at the i-site of bc1 complex. Biochimica et Biophysica Acta 976(2-3): 182-189

The concept of a stabilized semiquinone radical forming the basis of a two-electron gate has long been familiar in the context of the quinone-reducing site in photosynthetic systems and has already been suggested to play a role at the i-site of the bc1-type complexes. It is here pointed out that this concept is sufficient to explain the so-called triphasic reduction kinetics of cytochrome bH, in which cytochrome bH goes partially reduced, is reoxidized and then goes fully reduced. The rate constants for binding and unbinding of quinone, quinol and semiquinone at the i-site are discussed, and a kinetic model featuring slow release of the i-site semiquinone is shown to display many features of the kinetics of electron transfer at the i-site.


PMID: 2551386

Other references

Jackson, S.F.; Birn, A-Emanuelle.; Fawcett, S.B.; Poland, B.; Schultz, J.A., 2015: Synergy for health equity: integrating health promotion and social determinants of health approaches in and beyond the Americas. Health promotion and social determinants of health approaches, when integrated, can better contribute to understanding and addressing health inequities. Yet, they have typically been pursued as two solitudes. This paper presents the key elements,...

Price, B.; Liner, A.L.; Park, S.; Leppla, S.H.; Mateczun, A.; Galloway, D.R., 2001: Protection against lethal anthrax toxin challenge by genetic vaccination with plasmids that encode B anthracis protective antigen and/or a mutant form of lethal factor. The ability of genetic vaccination to protect against a lethal challenge of anthrax toxin was evaluated. Balb/c mice were immunized via gene gun inoculation with eucaryotic expression plasmids encoding either the protective antigen (PA), a mutated...

Elfath, M.; Sawyer, S.; Whitley, P.; Mcneil, D.; Hupp, K.C.; Bell Dize, S.; Mcateer, M., 1997: In vivo and in vitro evaluation of platelets collected using the new COBE Trima system. Transfusion (Bethesda) 37(9 SUPPL ): 6S

Wheeler, G.L.; Jones, M.A.; Smirnoff, N., 1998: The biosynthetic pathway of vitamin C in higher plants. Vitamin C (L-ascorbic acid) has important antioxidant and metabolic functions in both plants and animals, but humans, and a few other animal species, have lost the capacity to synthesize it. Plant-derived ascorbate is thus the major source of vita...

Yang, P.; Xiang, Y.; Lin, Z.; Lang, Z.; Jiménez-Lozano, P.; Carbó, J.J.; Poblet, J.M.; Fan, L.; Hu, C.; Kortz, U., 2016: Discrete Silver(I)-Palladium(II)-Oxo Nanoclusters, {Ag 4 Pd 13 } and {Ag 5 Pd 15 }, and the Role of Metal-Metal Bonding Induced by Cation Confinement. NlmCategory="UNASSIGNED">We introduce the class of discrete silver(I)-palladium(II)-oxo nanoclusters with the preparation of {Ag<sub>4</sub> Pd<sub>13</sub> } and {Ag<sub>5</sub> Pd<sub>15<...

Schuz, E., 1936: XXIX. Bericht (1935) der Vogelwarte Rossitten der Kaiser Willielm-Gesellschaft zur Forderung der Wissenschaften. Vogelzug Berlin, 7: 68-78

Thomason, M.J.; Rhys Williams, W.; Hutt, A.J.; Lloyd, A.W.; Hanlon, G.W., 1996: Demonstration of the chiral inversion of ibuprofen by Verticillium lecanii in non-growing cultures. Racemic ibuprofen has previously been shown to undergo metabolism by Verticillium lecanii to yield (S)-2-(4-(2-hydroxy-2-methylpropyl)phenyl) propionic acid which is enriched in the (S)-enantiomer. However, it had not been possible to elucidate wh...

Brigham, G.D.; Dyer, R.E., 1938: Endemic Typhus Fever in Native Rodents. A brief annotation in which reference is made to the susceptibility of dogs, cats, hedgehogs, and pigeons, in addition to g. pigs, to infection with tibe virus of exanthematic typhus. An account is given of rodents which were found to be susceptib...

Pohl Jean, 1983: Playing with the Z-model. Meteoritics 18(4): 376

Smith, D.H.; Theakston, R.D., 1970: Comments on the ultrastructure of human erythrocytes infected with Plasmodium malariae. Annals of Tropical Medicine and Parasitology 64(3): 329-329