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Use of prazosin in the treatment of heart failure in patients with post-infarction cardiosclerosis


, : Use of prazosin in the treatment of heart failure in patients with post-infarction cardiosclerosis. Kardiologiia 30(12): 13-15

The study was undertaken to examine the effects of prazosin on clinical manifestations of the disease, hemodynamic parameters and myocardial contractility in 33 patients with coronary heart disease, postinfarction cardiosclerosis. The study was performed during an acute and chronic drug test. The efficiency of the therapy was checked by conventional clinical tools and examination of hemodynamic parameters and myocardial contractility from echocardiographic evidence. In the acute and chronic drug test, prazosin was found to cause a significant reduction in systemic and pulmonary pressures, total peripheral resistance and an improvement of total and regional myocardial contractility. Its two- or three-week therapy suffices to achieve the steady therapeutic effect of the drug.

US$29.90

PMID: 2097387


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Kunitsa, A.A.; Bravaya, K.B., 2016: First-Principles Calculations of the Energy and Width of the (2)A(u) Shape Resonance in p-Benzoquinone: A Gateway State for Electron Transfer. Quinones are versatile biological electron acceptors and mobile electron carriers in redox processes. We present the first ab initio calculations of the width of the (2)A(u) shape resonance in the para-benzoquinone anion, the simplest member of th...

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Wheat, C.W.; Fescemyer, H.W.; Kvist, J.; Tas, E.; Vera, J.Cristobal.; Frilander, M.J.; Hanski, I.; Marden, J.H., 2011: Functional genomics of life history variation in a butterfly metapopulation. In fragmented landscapes, small populations frequently go extinct and new ones are established with poorly understood consequences for genetic diversity and evolution of life history traits. Here, we apply functional genomic tools to an ecological...

Zheng, Y.; Zhang, N.; Lu, W.; Zhang, L.; Gu, S.; Zhang, Y.; Yi, X.; Hua, K., 2017: Rectovaginal fistula following surgery for deep infiltrating endometriosis: Does lesion size matter?. Objective This study was performed to identify risk factors for postoperative rectovaginal fistula (PRF) in patients with deep infiltrating endometriosis (DIE). Methods Data were retrospectively obtained from the medical records of 104 patients wi...

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