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A comparison of the bioavailability of two carbamazepine preparations (200 and 400 mg tablets)


, : A comparison of the bioavailability of two carbamazepine preparations (200 and 400 mg tablets). Journal of International Medical Research 12(2): 108-113

A 2-week open, randomized, crossover study was conducted in epileptic patients on chronic therapy, who took either carbamazepine (CBZ) 200 or CBZ 400 mg tablets. The oral dose was 1200 or 1600 mg/day, according to individual needs. There was no difference in absorption or steady-state levels between the two preparations. The new galenic preparation of CBZ will help the neurologist to reduce the number of tablets taken by severe epileptic patients, with no risk but only benefits for the subjects.

US$29.90

PMID: 6724125


Other references

Liu H.M.; Atack J.R.; Rapoport S.I., 1989: Immunohistochemical localization of intracellular plasma proteins in the human central nervous system. The regional distribution of plasma protein immunoreactivity was studied in the postmortem central nervous system (CNS) of normal subjects 18 to 78 years old. Samples taken from various areas of brain and spinal cord were processed for peroxidase-...

Lovkova, M.; Il'-In, G.; Minozhedinova, N., 1973: Nicotine transformation to anabasine in Nicotiana glauca shoots. Prikladnaia biokhimiia i mikrobiologiia: 9 (4) 595-598

Iho, S.; Takahashi, T.; Kura, F.; Sugiyama, H.; Hoshino, T., 1986: The effect of 1,25-dihydroxyvitamin D3 on in vitro immunoglobulin production in human B cells. 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) dose-dependently suppressed immunoglobulin (Ig) production of human B cells, as evaluated by IgG-plaque-forming cells (IgG-PFC) in the culture of pokeweed mitogen (PWM)-activated B cells. Similar suppressive...

Abrahamsen, G., 1971: The influence of temperature and soil moisture on the population density of Cognettia sphagnetorum (Oligochaeta: Enchytraeidae) in cultures with homogenized raw humus. Pedobiologia 1 (5) 417-424

Cohen Solal, A.; Jondeau, G.; Duc, P.; Witchitz, S.; Berdeaux, A., 2001: Beneficial effects of carvedilol on angiotensin-converting enzyme and renin activities escapes in patients with chronic heart failure. Journal of the American College of Cardiology 37(2 Supplement A): 280A, February

Vigil E.L., 1989: Minisymposium on histochemistry of botanical samples held at the 8th international congress of histochemistry and cytochemistry. Cell Biology International Reports 13(1): 1-152

Katz, B.A.; Stroud, R.M.; Collins, N.; Liu, B.; Arze, R., 1995: Topochemistry for preparing ligands that dimerize receptors. The cyclic, disulfide-containing peptide, cyclo-Ac-[Cys-His-Pro-Gln-Gly-Pro-Pro-Cys]-NH2, binds to streptavidin with high affinity. In streptavidin-peptide cocrystals of space group I222, cyclic peptide monomers are bound on adjacent streptavidin...

Chung, R.S., 1989: Videoendoscopy for difficult anastomoses. To determine whether intra-operative videoendoscopy provides useful information on the integrity of gastrointestinal anastomoses, laboratory and clinical studies were undertaken. In the dog model, the videoendoscope was inserted per orum to visual...

Fromtling, R.A.; Fromtling, A.M.; Staib, F.; Müller, S., 1981: Effect of uremia on lymphocyte transformation and chemiluminescence by spleen cells of normal and Cryptococcus neoformans-infected mice. The effect of uremia on immune incompetence was studied. BALB/c mice were infected with a minimally virulent strain of Cryptococcus neoformans 6 weeks before immune assay. Uremia was induced by intramuscular injection of 0.15 ml of glycerol. Poole...

Jandl, H.; Schielke, U.; Rössner, B.; Wessel, G.; In der Au, A.; Jäckel, R.; Römhild, N.; Keitel, W.; Wenz, W.; Bartuschka, B.; Altus, R.; Tanner, E.; Wesser, M.; Zielke, A.; Lindau, P., 1979: Antinuclear factors. Beitrage Zur Rheumatologie 23: 124-128