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A new method with high sensitivity and specificity for localization of abnormal parathyroid glands


, : A new method with high sensitivity and specificity for localization of abnormal parathyroid glands. Annals of Surgery 200(3): 381-388

A novel method for localization of abnormal parathyroid glands involving color-processing of nuclear scintigrams of the neck after injection of Thallium-201 and Technetium pertechnetate is presented with surgical correlation. Preoperative localization of single parathyroid adenomas was successful in 88% of previously unoperated patients and in 85.7% of those with adenomas not located at previous surgery. Eighty-three per cent of glands with secondary hyperplasia, 66% of glands with primary hyperplasia, and one carcinoma were localized. No abnormal studies were seen in non-hyperparathyroid hypercalcemia, and no false positive studies were seen. Localization appeared related to larger adenomas (300-5000 mg), although one of 60 mg was localized. Color-comparison dual-isotype scintigraphy was useful for localization of parathyroid adenomas and hyperplastic glands and exceeded the reported sensitivity of either ultrasonography or computerized tomography. It deserves wider evaluation in preoperative management of at least hyperparathyroidism of the primary or persistent types.

US$29.90

PMID: 6087747


Other references

Bresler, L.; Vidrequin, A.; Poussot, D.; Mangin, P.; Pinelli, G.; Boissel, P.; Grosdidier, J.; Claudon, M., 1989: Fistulous communication of a pancreatic pseudocyst with the common bile duct: demonstration by operative cholangiogram. American Journal of Gastroenterology 84(7): 835-836

Kafl, H.E.; Elkashef, H.A., 2006: Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats. Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats was investigated. Vanadate concentrations of 0.1, 0.5 and 1 mM produced a concentration-dependant increase in isolated urinary bladder tension...

Anonymous, 1964: Annual report of the Ministry of Agriculture of the Republic of Zambia for the year 1964. Varietal trials were performed on coffee, tea, Burley tobacco, cotton and maize. Maize. When Hickory King was compared with SR2, a single hybrid, at four localities under conditions of low fertility, it was found that SR2 outyielded Hickory King....

Taylor, Pm, 2002: Intravenous versus inhalation anesthesia. Proceedings of the North American Veterinary Conference6(16): 145-146

LePennec, J.P.; Baldacci, P.; Perrin, F.; Cami, B.; Gerlinger, P.; Krust, A.; Kourilsky, P.; Chambon, P., 1978: The ovalbumin split gene: molecular cloning of Eco RI fragments "c" and "d". The Eco RI fragments "c" and "d" of the ovalbumin gene (1, 2) have been isolated by molecular cloning. Restriction enzyme mapping and electron microscopy have confirmed that the two fragments contain the same ovalbumin mRNA cod...

Brundage, M.; Sydes, M.R.; Parulekar, W.R.; Warde, P.; Cowan, R.; Bezjak, A.; Kirkbride, P.; Parliament, M.; Moynihan, C.; Bahary, J-Paul.; Parmar, M.K.B.; Sanders, K.; Chen, B.E.; Mason, M.D., 2015: Impact of Radiotherapy When Added to Androgen-Deprivation Therapy for Locally Advanced Prostate Cancer: Long-Term Quality-of-Life Outcomes From the NCIC CTG PR3/MRC PR07 Randomized Trial. The NCIC CTG PR3/MRC PR07 randomized phase III trial compared androgen-deprivation therapy (ADT) alone versus ADT with radiotherapy (RT) for patients with locally advanced prostate cancer. This article reports the health-related quality-of-life (H...

Chamley, J.H.; Mark, G.E.; Campbell, G.R.; Burnstock, G., 1972: Sympathetic ganglia in culture. I. Neurons. Zeitschrift für Zellforschung und Mikroskopische Anatomie 135(3): 287-314

Anonymous, 1954: New fire proofing agents.. A water-insoluble NH4 compound is mixed with a binder so as to obtain a mass that can be brushed or sprayed, after which one or more acid salt and nitrites or nitrates and/or organic nitro or nitrosocompounds are added.

Walker, E.K., 1974: Comparison of flue-cured tobacco transplants variable in procedures for hardening. Transplanted tobacco seedlings from seed sown at different rates and which had been exposed to different hardening treatments varied considerably in survival and rate and uniformity of early growth in the field. Rate and uniformity of early growth...

Edwards, C.L.; Johnson, S.; Goli, V.; Byrd, G., 2005: Extending the science beyond medication: in response to "Treatment of chronic pain in persons with dementia: an overview" by Robert N. Rubey, MD, MA. American Journal of Alzheimer's Disease and Other Dementias 20(3): 139-40; Author Reply 140