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A new model for investigation of transluminal recanalization: human atherosclerotic coronary artery xenografts

, : A new model for investigation of transluminal recanalization: human atherosclerotic coronary artery xenografts. American Journal of Cardiology 54(1): 200-205

A model for testing transluminal recanalization techniques was developed. Human atherosclerotic arteries were transplanted in dogs and evaluated by angiographic and histologic study within a 12-week period. An inflammatory response was most intense within the first 2 weeks. By 12 weeks, no inflammation was noted. The model has several advantages: (1) The pathologic characteristics are those of a human coronary artery. (2) Thrombus formation is frequent, with progression to a well organized dense fibrocellular vascular occlusion within 4 to 12 weeks. (3) The arterial occlusion resembles human vascular disease. (4) The vascular occlusions are readily accessible with standard catheterization technique. (5) The model is easy to produce within a short period. This model has been used to evaluate laser recanalization of vascular obstructions.


PMID: 6741814

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Rachou, R.G.; Neves, H.A.; Scaff, L.M., 1955: Use of Hetrazan in short courses to combat filariasis. Diethyl carbamazine in daily doses of 6 mg/kg three times/day for 7-10 days produced a great reduction in microfilarial density, and a level of 15% of the pretreatment number was maintained for 18 months. Only 20% of observed carriers showed any m...

Jones, T.E., 2006: The five questions dentists should ask about their dollar and why. Question #2. What are your values and beliefs about money?. Journal - Oklahoma Dental Association 97(8): 22-23

Bradshaw C.W.; Shen G J.; Wong C H., 1991: A new alcohol dehydrogenase with unique stereospecificity from pseudomonas sp. A new nicotinamide cofactor-dependent alcohol dehydrogenase from Pseudomonas strain SBD6 (PADH) was isolated and purified 150-fold to homogeneity using a combination of salt precipitation, anion-exchange chromatography, gel filtration chromatograp...

Kramer M., 1984: Pyrazolones their hematologic side effects and the toxicological significance of their nitrosation. Rainsford, K D And G P Velo (Ed ) Advances in Inflammation Research, Vol 6 Side Effects Of Antiinflammatory/Analgesic Drugs Xiv+306p Raven Press: New York, N Y , Usa Illus P275-282

Koprowski,J.L.; King,S.R.B.; Merrick,M.J., 2008: Expanded home ranges in a peripheral population space use by endangered Mt Graham red squirrels. Peripheral populations are often of increased conservation value; however, knowledge of the ecological and evolutionary consequences of a peripheral location is poor. Spatial dynamics are often interpreted as strategies to maximize access to fitne...

Dorello, Primo., 1907: Contribute allo studio dello sviluppo del nucleo rosso (Nucleus tegmenti)negli embrioni di Maiale. Roma Bend Acc Lincei ser 5: 16 84-90

Morris, P.R.bbins, M., 1992: Condensed tannin formation by Agrobacterium rhizogenes transformed root and shoot organ cultures of Lotus corniculatus. Journal of experimental botany 43(247): 221-231

Brown, S.M.; Szewc Mcfadden, A.K.; Kresovich, S., 1996: Development and application of simple sequence repeat loci for plant genome analysis. Jauhar, P P [Editor] Methods of genome analysis in plants : 147-159

Doerr, E.D.; Doerr, V.A.J.; Safran, R.J., 2007: Integrating delayed dispersal into broader concepts of social group formation. Intratumoral granulomas and granulomas in lymph nodes draining breast carcinomas have been reported previously. However, in regions like Pakistan, where the incidence of tuberculosis (TB) is high, it is sometimes difficult to distinguish between T...

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