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A sensitive human thyroglobulin RIA to define clearly the presence or absence of functioning thyroid tissue


, : A sensitive human thyroglobulin RIA to define clearly the presence or absence of functioning thyroid tissue. Journal of Nuclear Medicine 25(1): 49-55

This paper describes a practical procedure to establish a sensitive radioimmunoassay for the measurement of human thyroglobulin (HTg) in serum. The assay enables a clear distinction to be made between levels of HTg indicating the presence or absence of functioning thyroid tissue. It compares the use of HTg serum levels with the conventional I-131 scintigram as a marker for recurrent thyroid cancer. In addition, a simple and sensitive radioimmunologic assay is described for the determination of serum antithyroglobulin autoantibodies, the presence of which may give falsely elevated HTg levels.

US$29.90

PMID: 6726420


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