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A sequence related to 4.5 S RNA and the B1 family of repeated DNA in the 5' flanking region of the mouse beta-globin gene


, : A sequence related to 4.5 S RNA and the B1 family of repeated DNA in the 5' flanking region of the mouse beta-globin gene. Journal of Molecular Biology 169(4): 975-982

A beta-globin gene probe containing 5' flanking DNA hybridizes to a small nuclear RNA from Friend erythroleukemia cells, which was subsequently identified as 4.5 S RNA. This hybridization is shown to reflect complementarity between the Alu consensus region of 4.5 S RNA and the DNA sequence between nucleotides -33 and -48 from the beta-globin gene transcription initiation site.

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PMID: 6195342


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