geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A sequential study of humoral factors in ovarian neoplasms


, : A sequential study of humoral factors in ovarian neoplasms. Indian Journal of Pathology & Microbiology 37(3): 319-326

A sequential study of serum immunoglobulins, circulating immune-complexes (CIC) and blocking effect of patients' sera on normal T lymphocytes was conducted in 15 patients with benign ovarian tumour, 32 with carcinoma ovary and 20 agematched healthy women. In patients with benign ovarian tumour there was a significant increase in IgG and IgM, while IgA was not altered. In carcinoma, there was no significant change in IgG and IgM but IgA was found to be increased significantly as compared to benign ovarian tumour. Post-operatively, IgM showed a significant increase on the 10th day, probably due to the effect of surgery. There was no significant difference in CIC levels and percentage T cell depression between patients with benign ovarian tumours and healthy controls. In carcinoma ovary both these parameters were increased significantly as compared to benign ovarian tumours. After tumour ablation, they were decreased significantly, until there was recurrence. The alterations in these parameters was not related to any specific histologic type of neoplasm. The study of serum immunoglobulins indicates tumour load, while the estimation of CIC and blocking effect of cancer sera on normal lymphocytes is of a definite diagnostic and prognostic significance.

US$29.90

PMID: 7814065


Other references

Dussault, P.E.; Lepage, M., 1978: Influence of pyridoxine deficiency on the metabolism of fatty acids in rats. The effect of pyridoxine deficiency on rat liver fatty acid synthetase was studied using acetyl-1-14C-CoA. No significant difference was observed in the synthetase activity between the deficient and ad lib control rats. From in vivo experiments wi...

Unger, J.; McNeill, T.H.; Moxley, R.T.; White, M.; Moss, A.; Livingston, J.N., 1989: Distribution of insulin receptor-like immunoreactivity in the rat forebrain. Previous studies have suggested that insulin may play a role in the hormonal regulation of neurotransmitter metabolisms within the central nervous system. In order to provide additional information to support this hypothesis, we examined the distr...

Tybusz, R.; Dettlaff, Z., 1966: Effect of penicillin and penicillin with hydrazines on Mycobacterium tuberculosis in vitro. Gruzlica i Choroby Pluc; Tuberculosis et Pneumonologia 34(7): 627-629

de Laubenfels, M.W., 1937: A Case Of Incorrect Identification. The sponge which occurs along the Atlantic coast of N. America, long supposed to belong to the genus Grantia, is really Scypha coronata Ell. and Solander.

Andreev A.V., 1988: Ecological energetics of palearctic tetraonidae in relation to chemical composition and digestibility of their winter diets. Parameters of digestion and energetics of free-living grouse were plotted against body mass to determine whether a general relationship exists between quantitative food intake, digestibility, and energy demands of individuals of different sizes, a...

Leedge Plegt, L.M. van der; Kronenburg van der Ven, B.C.E.; Franken, J.; Tuyl, J.M. van; Tunen, A.J. van; Dons, H.J.M., 1997: Transgenic lilies via pollen-mediated transformation. A particle gun was used for the introduction of the NPTII gene (for kanamycin resistance) into pollen of lily (Lilium longiflorum) cv. Gelria. Subsequently, the bombarded pollen was used for pollination of flowers of cv. Indian Summer. A large num...

Dubernet, J.; Casanegra, P.; Irarrazaval, M.; Maturana, G.; Morán, S.; Turner, E.; González, J.A.; Lema, G.; Urzua, J., 1987: Reinterventions on cardiac valve prostheses. Annales de Chirurgie 41(2): 110-115

Slowiaczek, L.M.; Klayman, J.; Sherman, S.J.; Skov, R.B., 1992: Information selection and use in hypothesis testing: what is a good question, and what is a good answer?. The process of hypothesis testing entails both information selection (asking questions) and information use (drawing inferences from the answers to those questions). We demonstrate that although subjects may be sensitive to diagnosticity in choosi...

Southron, J.L.; Taylor, G.J., 2001: A Brassica napus putative copper-transporting P-type ATPase expressed in Saccharmoyces cerevisiae. Plant Biology (Rockville) : 99

Colloms, S.D.; Alen, C.; Sherratt, D.J., 1998: The ArcA/ArcB two-component regulatory system of Escherichia coli is essential for Xer site-specific recombination at psi. Two recombinases, XerC and XerD, act at the recombination sites psi and cer in plasmids pSC101 and ColE1 respectively. Recombination at these sites maintains the plasmids in a monomeric state and helps to promote stable plasmid inheritance. The ac...