geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1


, : A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1. Journal of Biological Chemistry 257(24): 14865-14874

A series of glycolipid antigens reacting with the monoclonal antibody directed to the stage-specific embryonic antigen 1 was isolated and characterized from group O human erythrocyte membranes. A ceramide heptasaccharide (Structure 1), ceramide nonasaccharide (Structure 2), and ceramide decasaccharide (Structure 3) have been characterized (formula, see text) The main feature of this glycolipid series is its long core sugar chain with a nonbranched repeating N-acetyllactosamine (norpolylactosamine). This characteristic is in contrast to that of co-existing H-active glycolipid series in which the longer core structures are branched type repeating N-acetyllactosamine (isopolylactosamine). The reactivity of these glycolipids to monoclonal anti-stage-specific embryonic antigen 1 antibody varied proportionately to the length of their core sugar chains. A possible significance of these glycolipids as developmentally regulated antigens and as cancer-associated antigens was discussed.

US$29.90

PMID: 6129244


Other references

Freile-Pelegrin, Y.; Robledo, D.; Pedersen, M.; Bruno, E.; Ronnqvist, J., 2002: Efecto del tratamiento de oscuridad y salinidad en el rendimiento y calidad del agar de Gracilaria cornea (Rhodophyceae). The alkali treatment used previous to agar extractions from the Gracilaria genus reduces, among other reactions, the sulphate content and improves the gel strength; however, at an industrial level it requires expensive effluent processing to reduc...

Grinina, O.V., 1973: Scientific studies of the Department of Social Hygiene and Public Health Organization. Zdravookhranenie Rossiiskoi Federatsii 17(3): 27-32

Kordes, W., 1997: Variety: 'Spekes' syn Our Sacha. Application no: 96/080. A brief description is provided for this upright, bushy, bedding rose (Rosa) cultivar, derived as a spontaneous mutation or sport in Korcrisett and selected on the basis of improved cut flower production under greenhouse conditions. Spekes produce...

Hacker, H.J.; Bannasch, P.; Liehr, J.G., 1988: Histochemical analysis of the development of estradiol-induced kidney tumors in male Syrian hamsters. Chronic administration of the estrogen 17 beta-estradiol induces kidney tumors in male Syrian hamsters within 6 months of initial exposure. Although these tumors have previously been studied histologically and histochemically and have been postula...

Balla, J., 2006: Energetic parameters of abrasive wear. An experiment was conducted to investigate energy consumption during the abrasive wear process performed in various conditions in relation to the intensity of wear. A test apparatus based on pin-on-disc configuration with abrasive cloth was used....

Mascle Jean, 1971: Marine geology of the Toulon canyon. Cahiers Oceanographiques 23(3): 241-250

Chawla, H.Singh.; Suri, S.; Utreja, A., 2007: Engagement of elastomeric modules for efficient force delivery. Journal of Clinical Orthodontics 40(11): 652-654

Drake L.A., 1991: SUCOGG - the Sydney Universities Consortium of Geology and Geophysics. Geophysics Down Under 14: 16-17

Rouchy J.M., 1974: Geological study of the upper valley of the Orb River, Herault; basement-cover relations; problems of silicification and baritic mineralization. Bulletin du Museum National d'Histoire Naturelle 214): 1-93

Jensen, O.T.; Leopardi, A.; Gallegos, L., 2004: The case for bone graft reconstruction including sinus grafting and distraction osteogenesis for the atrophic edentulous maxilla. Journal of Oral and Maxillofacial Surgery 62(11): 1423-1428