geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A serum-dependent defect of neutrophil function in chronic mucocutaneous candidiasis


, : A serum-dependent defect of neutrophil function in chronic mucocutaneous candidiasis. Journal of Clinical Pathology 33(4): 370-372

Investigations into the immunological functions of three patients with chronic mucocutaneous candidiasis were carried out. Phagocytosis of Candida albicans, nitroblue tetrazolium dye reduction, complement, and immunoglobulin levels were normal. Candidacidal assays using the neutrophils of the patients in autologous serum showed significant decreases below normal levels. This decrease in kill could be corrected by incubating the patients' cells in normal control or human AB serum. Cross-over serum studies also showed that the patients' sera had inhibitory effects on the candidacidal capacity of normal neutrophils. These changes in kill were related to candida antibody levels.

US$29.90

PMID: 6995490


Other references

Munteanu, C.R.; Dorado, J.; Pazos, A., 2014: Artificial intelligence techniques in medicinal chemistry. Current Topics in Medicinal Chemistry 13(5): 525-525

Varady, C., 1976: Recommended list of cereal cultivars. The parentage, breeding station, grain yield and quality, maturity, plant height, disease resistance and general characteristics of 5 winter barley, 1 winter rye, 2 winter oat, 5 spring oat, 10 maize, 6 winter wheat and 6 spring wheat cultivars on...

Nedwin, G.E.; Mohler, M.A.; Luben, R.A., 1984: Production of human/mouse hybridomas secreting a human lymphokine, osteoclast activating factor. A human/mouse hybridoma was developed which has the property of secreting a human bone resorbing factor similar or identical to the osteoclast activating factor (OAF) isolated from human tonsil lymphocytes. Mouse plasmacytoma cells negative for OA...

Izrailtyan, I.; Clark, J.; Swaminathan, M.; Podgoreanu, M.V.; Mackensen, B.; Davis, R.Duane.; Mathew, J.P., 2006: Case report: optimizing intraoperative detection of pulmonary embolism using contrast-enhanced echocardiography. Perioperative pulmonary embolism (PE) is associated with significant morbidity and mortality. Intraoperatively, the clinical management of patients with PE can be enhanced by the use of transesophageal echocardiography (TEE) to visualize emboli, a...

Wexler, M.J.; Olak, J., 1987: Resection of the liver for metastatic disease. Canadian Journal of Surgery. Journal Canadien de Chirurgie 30(4): 229-229

Necchi, V.; Candusso, M.Elena.; Tava, F.; Luinetti, O.; Ventura, U.; Fiocca, R.; Ricci, V.; Solcia, E., 2007: Intracellular, intercellular, and stromal invasion of gastric mucosa, preneoplastic lesions, and cancer by Helicobacter pylori. Background & Aims: It is not clear how Helicobacter pylori, an apparently extracellular pathogen colonizing the luminal side of the gastric epithelium, invariably causes an immune-inflammatory response on the stromal side of the mucosa. Penetrati...

Zhou, C.; Ziegler, C.; Birder, L.A.; Stewart, A.F.R.; Levitan, E.S., 2006: Angiotensin II and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA. Pathological and physiological hypertrophy of the heart is associated with decreased expression of the Kv4.3 transient outward current (I-to) channel. The downregulation of channel mRNA and protein, which may be proarrhythmic, is recapitulated wit...

Wenz, W.; Kotoulas, K., 1979: Radiologic findings on crohn's disease of the adult. Roentgen signs of 42 patients with Crohn's disease are reported. Characteristic features are stenosis [30], fistulas (30), cobble-stone formation (14), asymetry of lesions (12), and thickening of the mucosal wall (10). Main locations are the...

Rosander, K.; Sims, L., S., 1981: Measuring effects on an affective-based nutrition education intervention. An affective-based nutrition education program was developed to improve dietary behavior of WIC program participants by focusing on their nutrition and health attitudes. Three lessons related appropriate intakes of calcium, iron, and folacin to th...

Giam, C.S.; Chan, H.S.; Neff, G.S., 1978: Phthalate ester plasticizers ddt dde and poly chlorinated bi phenyls in biota from the gulf of mexico. The levels of phthalate ester plasticizers, DDT, DDE and polychlorinated biphenyls (PCB) were determined in the tissues of 18 species of marine organisms from the northwestern Gulf of Mexico. Low levels of the most widely used phthalate, di-(2-eth...