+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Activity of a new long-acting anti-arrhythmic drug on ventricular extrasystole. Study with Holter continuous electrocardiographic monitoring

, : Activity of a new long-acting anti-arrhythmic drug on ventricular extrasystole. Study with Holter continuous electrocardiographic monitoring. Giornale Italiano di Cardiologia 11(5): 657-662

Therapeutic effectiveness of a new long-acting antiarrhythmic preparation was evaluated in 31 patients with sustained premature ventricular beats. After an observation period, a 24 hours Holter monitoring was performed. A group (21 patients) was treated with dihydrochinidine 250 mg twice a day; another group (11 patients) was treated with 500 mg twice a day. In the latter group was determined basal chinidinemia on the first and third day. A 24 hours Holter monitoring was repeated on the fourth day. In the first group we reached a 77.4% reduction of the arrhythmia: not enough, however, to agree with established statements. We reached a larger reduction (84.7%) with higher doses (1000 mg daily). This drug was well tolerated in both groups.


PMID: 6169582

Other references

Hobday, F., 1922: Urinary Calculi in Animals. Proceedings of the Royal Society of Medicine 15(Sect Urol): 69-72

Palm, W.; Hockemeyer, D.; Kibe, T.; de Lange, T., 2008: Functional dissection of human and mouse POT1 proteins. The single-stranded telomeric DNA binding protein POT1 protects mammalian chromosome ends from the ATR-dependent DNA damage response, regulates telomerase-mediated telomere extension, and limits 5'-end resection at telomere termini. Whereas m...

Fabricant, N.D., 1953: Importance of pH values in nasal medication. Eye, Ear, Nose & Throat Monthly 32(5): 265-266

Macruz, R.; Ribeiro, M.P.; Brum, J.M.; Pasqualucci, C.A.; Mnitentag, J.; Bozinis, D.G.; Marques, E.; Jatene, A.D.; D'ecourt, L.V.; Armelin, E., 1985: Laser surgery in enclosed spaces: a review. We describe the results of experiments carried out in the arteries of dogs, rabbits, guinea pigs, and humans, normal or atheromatous, calcified, or not, with the application of the argon and CO2 laser, in vitro or in vivo, directly or indirectly....

Ehlers, C.L.; Somes, C.; Lumeng, L.; Li, T.K., 1999: Electrophysiological response to neuropeptide Y (NPY): In alcohol-naive preferring and non-preferring rats. Electroencephalograms (EEGs) and event-related potentials (ERPs) to auditory stimuli were recorded following intracerebroventricular administration of neuropeptide Y (saline, NPY: 1.0, 3.0 nmol) in two lines of rats that have been genetically sele...

Chou, C-Pin.; Huang, J-Shyung.; Wu, M-Ting.; Pan, H-Ben.; Huang, F-Dee.; Yu, C-Cheng.; Yang, C-Fang., 2005: CT voiding urethrography and virtual urethroscopy: preliminary study with 16-MDCT. The purpose of this study was to demonstrate CT voiding urethrography and CT virtual urethroscopy. Fourteen CT voiding urethrography examinations on 13 men (mean age, 30 years) were prospectively performed with 16-MDCT. The clinical diagnoses of t...

Bracken, C.A.; Gurkowski, M.A.; Naples, J.J., 1997: Lung transplantation: historical perspective, current concepts, and anesthetic considerations. Journal of Cardiothoracic and Vascular Anesthesia 11(2): 220-241

Engbersen, R.; Kramers, C., 2005: Enhanced extracorporeal elimination of valproic acid in overdose. The treatment of the poisoned patient has been based on three main approaches: use of supportive nonspecific therapy, if available administration of antidotes and removal of the offending drug from the body. Gastric lavage and binding of nonabsorb...

Altszuler N.; Rathgeb I.; Steele R.; Bjerknes C., 1970: Increased sensitivity of the hypophysectomized dog to the elevation in glucose release induced by di butyryl 3 5 cyclic amp. Federation Proceedings 29(2): 615

Foy, C.D., 1996: Tolerance of barley cultivars to an acid, aluminum-toxic subsoil related to mineral element concentrations in their shoots. Barley, Hordeum vulgare L., is extremely sensitive to excess soluble or exchangeable aluminum (Al) in acid soils having pH values below about 5.5. Aluminum tolerant cultivars are needed for use in rotations with potatoes which require a soil pH be...