+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Approximate dimensions of membrane lesions produced by streptolysin S and streptolysin O

, : Approximate dimensions of membrane lesions produced by streptolysin S and streptolysin O. Biochimica et Biophysica Acta 729(1): 115-122

Membrane lesions produced by the streptococcal membranolysins streptolysin S and streptolysin O were investigated. Escape of labeled marker molecules of various sizes from resealed sheep erythrocyte ghosts treated with the toxins for 30 min allowed estimation of the sizes of the primary channels formed. Streptolysin S formed lesions ranging in size up to 45 A in diameter, and even high toxin concentrations did not result in larger channels. The lesions produced by streptolysin O exceeded 128 A in diameter. Kinetics experiments demonstrated that the primary streptolysin O lesions were formed rapidly (1-2 min), but release of marker molecules from streptolysin S-treated vesicles began only after a 5-15-min lag period. Label release from large unilamellar liposomes treated with streptolysin S suggested that membrane fluidity does not affect the size of the streptolysin S lesions.


PMID: 6299345

Other references

Cretin, C.; Vidal, J.; Suzuki, A.; Gadal, P., 1984: Isolation of plant phosphoenolpyruvate carboxylase by high-performance size-exclusion chromatography. An immunoprecipitate of phosphoenolpyruvate carboxylase (PEPc) from leaves of Sorghum vulgare cv. INRA 450 produced 3 main protein bands on gel electrophoresis. The subunits of the immunogammaglobulins, separated by HPLC, were found to have molecu...

Flechtmann C.H.W., 1968: Mites of the cocoa d coffee d and tea d plants. Universidade de Sao Paulo Escola Superior de Agricultura "Luiz De Queiroz" Boletim Tecnico Cientifico 7: 1-11

Bari, M.; Rapino, C.; Mozetic, P.; Maccarrone, M., 2010: The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. Endocannabinoids (eCBs) include a group of lipid mediators that act as endogenous agonists at cannabinoid (CB(1), CB(2)) and vanilloid (TRPV1) receptors. In the last two decades a number of eCBs-metabolizing enzymes have been discovered that, toge...

Jacoby, M., 1904: Description of some new species of Phytophagous Coleoptera. Entomologist, 293-296

Schramm, T., 1961: Influence of fatty acids on carcinogenesis. I. Influence of fatty acids on carcinogenesis in the rat induced by 3-methyl-4-dimethylaminoazobenzene. Acta Biologica et Medica Germanica 6: 322-343

Taylor N.C.; Day J.W.Jr; Neusaenger G.E., 1989: Ecological characterization of jean lafitte national historical park louisiana usa basis for a management plan. U S Fish & Wildlife Service Biological Report 89(22): 247-277

Stadler, J.D.; Lotze, G.F.A., 1991: Suitability of certain plum and peach rootstocks for apricots. Various rootstocks suitable for use with apricot cultivars planted on shallow soils with a high pH, and waterlogged soils, were compared. Relatively high yield efficiency has been obtained with the apricot cultivars Palsteyn and Peeka in combinati...

Groth S.; Hald A.; Olesen H.P., 1985: External detection of pulmonary clearance of technetium 99m diethylenetriamine pentaacetic acid in the dog should recirculation be corrected for. American Review of Respiratory Disease 131(4 SUPPL): A340

Cliff, J.M., 1972: John Macfarlane Cliff. Lancet 2(7771): 286-286

Vartanian, A.A.; Turpaev, K.T.; NarovlianskiÄ­, A.N.; Amchenkova, A.M.; Kiselev, L.L., 1995: Interferons cause accumulation of diadenosine triphosphate (Ap3A) in human monocyte cultures. Doklady Akademii Nauk 344(2): 252-255