+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

C-AMP concentration in various organs of female rats and in human ovaries with aging

, : C-AMP concentration in various organs of female rats and in human ovaries with aging. Nihon Sanka Fujinka Gakkai Zasshi 34(2): 223-232

The change in 3',5'-cyclic adenosine monophosphate (c-AMP) concentration was observed in various organs of rats in gonadal cycle in adult group and with aging (30, 70, 100, 120 weeks), and in human ovaries with aging. 1) The average c-AMP concentration of ovaries of rats showed a significant change with estrus cycle and was higher in the following sequence: proestrus, diestrus II, diestrus I and estrus phase. This tendency was also seen in hypothalamus and pituitary, but was not statistically significant, 2) The average c-AMP concentration in tissues began to decline significantly from 70 weeks in cerebral cortex and hypothalamus, and from 80 weeks in ovaries. However, on the other hand the concentrations in pituitary, liver and adrenal declined markedly from 100 weeks. 3) The c-AMP in ovaries of 80 weeks rats by pregnant mare serum (PMS) road increased by 0.5-fold in concentration, and by 0.6-fold in whole tissue relative to that of 30 weeks rats. 4) A significant difference in serum LH and FSH level between ovarian artery and vein was not found in cycling mature group, non-cycling climacteric group and post-menopausal group of women. 5) Both average concentrations and total values of c-AMP in ovaries of non-cycling climacteric and post-menopausal women were lower than those of mature cycling women. This fact may imply a different response by ovarian tissues such as corpus luteum, follicle and other tissues to gonadotropin. From these results of c-AMP in tissues, it is concluded that the decline of ovarian function with aging of rats was relatively earlier than pituitary, although being delayed compared with hypothalamus, and were the ovarian function in humans declined in the premenopausal period.


PMID: 6278032

Other references

Wortis, J., 1982: Minister for the development of intelligence. Biological Psychiatry 17(5): 533-533

Palazon J.M.; Martin V.S., 1988: Enantioselective total synthesis of 6r 7r 3 cis 9 cis 12 cis 6 acetoxy 7 chloropentadeca 3 9 12 trien 1 yne and its 3 trans isomer. Tetrahedron Letters 29(6): 681-684

Anonymous, 1976: Community psychiatry. Krankenpflege 30(11): 322-323

Kusumi, K.; Fisher, R.E., 2013: Studying mechanisms of regeneration in amphibian and reptilian vertebrate models. Anatomical Record 295(10): 1529-1531

Langley, P., 1997: Scapular instability associated with brachial plexus irritation: a proposed causative relationship with treatment implications. Brachial plexus irritation and other compression neuropathies can be diverse in their presentations and can cause a myriad of signs and symptoms. The purpose of this paper is to review the pertinent anatomy, kinesiology, and neurophysiology and to...

Waisbren S.E.; Mahon B.E.; Levy H.L., 1985: Predictors of iq and iq loss in treated phenylketonuria. Pediatric Research 19(4 PART 2): 323A

McVey, E.M.; Hanfman, D.T.; Smith, M.F.; Young, A.T., 1989: Practical aquaculture literature II. A bibliography. This bibliography updates Bibliographies and Literature of Agriculture, No. 35 (issued August 1985). Most of this update is new material. The purpose of the bibliography is to provide sources of information on practical aquaculture literature. The...

Formanek, K.; Lindner, A.; Selzer, H., 1968: Testing of antihypertensive agents with prolonged effect. Wiener Klinische Wochenschrift 80(10): 185-191

Bloch, G.R.; Bloch, N.H., 1972: Traumatic and post-traumatic neuroses. Ims, Industrial Medicine and Surgery 41(10): 5-8

Shtrasburg, S.; Lidar, M.; Pras, M.; Gal, R.; Livneh, A.; B.S.inner, M.B.rk, JL.C.nners, LH.S.ldin, DC, 2008: The effect of a variety of anti-inflammatory drugs on murine amyloidogenesis. XIth International Symposium on Amyloidosis): 93-95