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Chromatographic and spectral properties of some aryl-substituted phencyclidine analogs

, : Chromatographic and spectral properties of some aryl-substituted phencyclidine analogs. Journal of Analytical Toxicology 7(5): 252-256

As part of a search for phencyclidine (PCP) antagonists, a series of eleven aryl-substituted PCP analogs were prepared and characterized. TLC and GC elution profiles of these derivatives are described in a number of systems allowing for the tentative identification of the PCP analogs. Further, MS, NMR, UV/vis and IR spectral tabulations are provided. Correlation of chromatographic character with physical organic structure parameters, such as those of Hammet, showed good predictability.


PMID: 6645410

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