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Control of the proestrus surge of prolactin and luteinizing hormone secretion by estrogens in the rat

, : Control of the proestrus surge of prolactin and luteinizing hormone secretion by estrogens in the rat. Endocrinology 89(6): 1448-1453

Oestradiol antiserum administered to female Sprague-Dawley rats on the'day of pro-oestrus immediately before the prolactin surge began haa no effect on subsequent prolactin or LH secretion, but when given 24 h earlier it abolished pro-oestrus surges of prolactin and LH and decreased ovulation and vaginal cornification. Simultaneous administration of die-thylstilboestrol with the Oestradiol antiserum prevented the inhibitory effects of antiserum.


PMID: 5166047

DOI: 10.1210/endo-89-6-1448

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