geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Correlation of echocardiographic wall stress and left ventricular pressure and function in aortic stenosis


, : Correlation of echocardiographic wall stress and left ventricular pressure and function in aortic stenosis. Circulation 67(4): 854-859

Previous studies have suggested that left ventricular pressure (P) can be predicted in patients with aortic stenosis by the equation P = 235 h/r, where 235 is a constant peak wall stress (sigma), h is end-systolic wall thickness, and r is end-systolic dimension/2; h and r are measured by M-mode echocardiography. In 73 patients with aortic stenosis (valve area less than 0.7 cm2), measured and predicted left ventricular pressure correlated poorly (r = 0.17). The measured wall stress in our patients varied from 120 to 250 mm Hg in patients with normal left ventricular function and from 250 to 550 mm Hg in patients with abnormal function. The correlation between sigma and h was only fair (r = 0.53), because many patients had inappropriate left ventricular hypertrophy. There was a statistically significant correlation between ejection fraction and sigma (r = 0.62) and between ejection fraction and end-systolic dimension (r = -0.70), but there was considerable scatter of ejection fractions for any given end-systolic dimension. We conclude that sigma is not constant in aortic stenosis, and the use of a constant sigma to predict left ventricular pressure is unreliable; inappropriate left ventricular hypertrophy may explain why sigma is not constant. M-mode echocardiography is not reliable in assessing the severity of aortic stenosis in adults; such assessment requires precise measurements of pressure gradients and flow by cardiac catheterization.

US$29.90

PMID: 6825239


Other references

Bensaid, M.; Fruchon, Séverine.; Mazères, C.; Bahram, S.; Roth, M-Paule.; Coppin, Hélène., 2004: Multigenic control of hepatic iron loading in a murine model of hemochromatosis. Background & Aims: Hereditary hemochromatosis is a common disorder of iron homeostasis characterized by increased dietary iron absorption and progressive iron accumulation, mainly in the liver. Most patients are homozygous for the C282Y mutation i...

Rundegren, J.; Ericson, T., 1981: Effect of calcium on reactions between a salivary agglutinin and a serotype c strain of Streptococcus mutans. Using a serotype c strain of Streptococcus mutans we found that the agglutinating activity could be quantitatively absorbed, and desorbed from the micro-organisms by a phosphate buffer. The desorbed agglutinin was found to be inactive in the absen...

Kuramoto, H.; Hata, H.; Kato, Y.; Hata, K.; Hamano, M.; Anzai, Y.; Watanabe, J.; Holinka, C.F.; Gurpide, E., 1989: Mechanism of action of endocrine therapy of endometrial carcinoma. The mechanism of action of sex steroid hormones on endometrial carcinoma was analyzed by a cell culture system. 1) Estrogenic actions such as enhancement of ALP activity, PR level and cellular growth were confirmed in Ishikawa endometrial carcinom...

Trumpowska, M.; Olszewski, Z., 1968: Chromatographic analysis of oils from Artemisia vulgaris L. obtained in different seasons. Acta Poloniae Pharmaceutica 25(3): 319-328

Helcl, J.; Janout, V.; Doubková, S.; Jurin, I.; Olejnĭk, O.; Valnicek, S.; Svandovă, E., 1971: Retrospective study of the incidence of viral hepatitis in patients operated under extracorporeal circulation. Journal of Hygiene, Epidemiology, Microbiology, and Immunology 15(3): 278-285

Kumar, E.S.S.nthosh; Yeragi, S.S.; Babu, K.N.; Khan, A.E.S.anavas, 2002: Pyrenacantha volubilis Hook A new record for Kerala state. Pyrenacantha volubilis Hook. is reported from Kerala for the first time. A brief description and illustration are also provided.

Lommerse, H., 2002: Dahlia plant named 'Dahlstar Violet'. A distinct cultivar of Dahlia plant named 'Dahlstar Violet', characterized by its upright and compact plant habit; freely branching, full and dense plants; medium-sized semi-double type inflorescences; purple-colored ray florets with bri...

Okada, M.; Nishimukai, H.; Okiura, T.; Sugino, Y., 2008: Lyonization pattern of normal human nails. To examine the X-inactivation patterns of normal human nails, we performed the human androgen receptor gene assay of DNA samples extracted separately from each finger and toe nail plates of nine female volunteers. The X-inactivation pattern of ea...

Prach, Karel, 2003: Spontaneous succession in Central-European man-made habitats: What information can be used in restoration practice?. The results of previous studies concerning spontaneous vegetation succession in various man-made or disturbed habitats in Central Europe are discussed in relation to restoration ecology. An attempt is made to answer the main questions which are im...

Trotter, J.A.; Purslow, P.P., 1992: Functional morphology of the endomysium in series fibered muscles. Many skeletal muscles, including the feline biceps femoris, are composed of short, tapered myofibers arranged in an overlapping longitudinal series. The endomysium of such muscles transfers tension between overlapping myofibers, and is thus an ela...