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Delayed neuropathy after organophosphorus insecticide (Dipterex) poisoning: a clinical, electrophysiological and nerve biopsy study


, : Delayed neuropathy after organophosphorus insecticide (Dipterex) poisoning: a clinical, electrophysiological and nerve biopsy study. Journal of Neurology, Neurosurgery, and Psychiatry 47(5): 543-548

Clinical, electrophysiological and histological findings in four patients accidentally poisoned with the organophosphorus insecticide Dipterex are reported. Three to five weeks after insecticide ingestion signs of a distal sensorimotor (preponderantly motor) neuropathy occurred. The patients complained of paraesthesia in the lower limbs, and two of them of very disagreeable pricking sensation in the soles of the feet, responsive to carbamazepine. They showed distal weakness mainly of the legs, footdrop , difficult gait and muscle hypotonia. Ankle jerk was abolished while other tendon reflexes persisted. Two months or even later after poisoning, knee jerks in all the patients were very brisk and more and less accompanied by other pyramidal signs (patellar clonus, abolishment of abdominal cutaneous reflexes, Babinski's sign). Clinical, electrophysiological and nerve biopsy data revealed a "dying-back" neuropathy in our patients. Distal muscle fatigue was confirmed by failure of neuromuscular transmission on repetitive nerve stimulation.

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PMID: 6736986


Other references

Kendrick, M.A.; Honda, M.; Phillips, D., 2009: Constraints on fluid-rock interaction and magmatic noble gas signatures in hydrothermal fluids. Geochimica et Cosmochimica Acta 73.13S: A639

Bartoloni C.; Dupont P.; Feltkamp H.; Johnston C.I.; Steinbach K.; Zilcher H.; Kaindl F., 1988: Ketanserin combined with a beta blocker or diuretic in essential hypertension a multicenter study. The antihypertensive effect of ketanserin 40 mg b.d. in combination with a beta-adrenergic blocking agent or a diuretic was assessed in an open study in 35 patients with essential hypertension, who had not responded to treatment with beta-blockers...

Fujii, N.; Shelat, A.; Hall, R., A.; Guy, R.K.plin, 2007: Design of a selective chemical probe for class IPDZ domains. Covalent labeling has been widely used for structural and functional analyses of proteins. To target a wide range of PDZ domains, we designed a chemical scaffold mimicking the E/D-T/S-XV peptide, which is a PDZ domain that binds ligands in higher...

Colvin, J., 1978: Soft, easy and flowing fashions. Spring 57 (3) 18-20

Mcgregor, Sl, 1986: Automated teller machines: their impact on Canadian families. Canadian home economics journaler 36(3): 118-121

Mackay, W.D., 1973: Treatment of breast cancer. 2. Nursing Mirror and Midwives Journal 136(17): 43-45

Swyer, G.I.M., 1942: The cholesterol content of normal and enlarged prostates. The Schultz reaction for cholesterol suggests that the adenomatous zones of enlarged prostates, and particularly the glandular elements thereof, contain a high cholesterol concentration, and that the cholesterol conc. of enlarged prostates is high...

Abstracts., 1994: Abstracts The American College of Veterinary Pathologists 45th annual meeting American Society for Veterinary Clinical Pathology 29th annual meeting Montreal, Quebec, Canada, October 30 - November 4, 1994. Veterinary Pathology. September; 315: 573-627

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