geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Determination of platelet factor 3 by thrombin generation using a micro-coagulation assay


, : Determination of platelet factor 3 by thrombin generation using a micro-coagulation assay. Thrombosis Research 27(3): 303-310

Platelet factor 3 activity is usually determined by the Stypven method in which factor Xa generation is measured indirectly. The determination is dependent on factors I, II, V, X in the test sample. A coagulation assay for platelet factor 3, which measures the thrombin generation promoted by platelet factor 3, is presented. The test depends on platelet factor 3 only, because factors II, Xa, V, fibrinogen and Ca++ are added in excess. The usability of the new method is shown by platelet factor 3 determinations in patients with various platelet diseases, after ingestion of aspirin and in samples of platelet concentrates before and after storage.

US$29.90

PMID: 6890246


Other references

Pisarenko, M.F.; Kaukhova, O.Ia.; Shablinskaia, E.M.; Karagioz, G.I.; Lopukhova, G.M., 1983: PUVA therapy in chronic dermatoses using a domestic photosensitizer. Vestnik Dermatologii i Venerologii: 52-55

Shiu Wan Ying; M.K.o Ching, 2000: Temperature dependence of physical-chemical properties of selected chemicals of environmental interest; I, Mononuclear and polynuclear aromatic hydrocarbons. Physical-chemical property data, which control air-water partitioning, namely vapor pressure, aqueous solubility and Henry's law constant over the environmentally relevant temperature range of 5-50 degrees C, are compiled and reviewed for the...

Nanda, A.; Chen, M-Hui.; Moran, B.J.; Braccioforte, M.H.; Dosoretz, D.; Salenius, S.; Katin, M.; Ross, R.; D'Amico, A.V., 2010: Total androgen blockade versus a luteinizing hormone-releasing hormone agonist alone in men with high-risk prostate cancer treated with radiotherapy. To assess whether short-course total androgen blockade vs. a luteinizing hormone-releasing hormone (LHRH) agonist alone affects the risk of prostate cancer-specific mortality (PCSM) in men with localized but high-risk disease treated with radiothe...

Gert D.C.uet, H.; Busquets Turner, L.; Gresham, A.; Ahearn, G.A., 1993: Electrogenic 2 sodium/1 proton antiport in crustacean epithelium is inhibited by a monoclonal antibody. We have previously published evidence that suggests that Na/H exchange in crustacean and echinoderm epithelia occurs by an electrogenic antiporter protein with two external cation binding sites that accommodate Na, amiloride, or Ca and display a 2...

Kuhn, K., 1993: Electronic documentation of images and findings in gastroenterology. Der Internist 34(3): 261-267

Dominguez, G.; Wilkins, G.; Thiemens, M.H., 2010: A fundamental approach to isotopic fractionations induced by thermal gradients in melts. Geochimica et Cosmochimica Acta 74.12, Suppl. 1: A239

Doug P.W.rd; Alex S.K.tt, 2009: Rangeland biodiversity assessment using fine scale on-ground survey, time series of remotely sensed ground cover and climate data an Australian savanna case study. Landscape Ecology 24(4): 495-507

Mccay, M.G., 2000: The effects of aerodynamic stability on the dynamics of tree frog gliding. Gliding has originated independently in at least two tree frog families, including the genus Agalychnis (family Hylidae). Gliding tree frogs of both families possess features such as enlarged, extensively webbed hands and feet and a unique gliding...

Heath M.E.; Hammel H.T., 1986: Body temperature and rate of oxygen consumption in chinese manis pentadactyla pangolins. Body temperatures and rates of O2 consumption and CO2 production were measured in four Chinese pangolins (Manis pentadactyla) during short-term exposures (2-4 h) to ambient temperatures (Ta) of 10-34.degree. C. At Ta < 27.degree. C the pangolin...

Syed, Z.; Cheepala, S.B.; Gill, J.N.; Stein, J.; Nathan, C.Ann.; Digiovanni, J.; Batra, V.; Adegboyega, P.; Kleiner, H.E.; Clifford, J.L., 2009: All-trans retinoic acid suppresses Stat3 signaling during skin carcinogenesis. Squamous cell carcinoma (SCC) of the skin is the most clinically aggressive form of nonmelanoma skin cancer. We have determined the effects of all-trans retinoic acid (ATRA), a naturally occurring chemopreventive retinoid, on signal transducer and...