+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Distribution of prostaglandin E2 and prostaglandin F2 alpha receptors in human myometrium

, : Distribution of prostaglandin E2 and prostaglandin F2 alpha receptors in human myometrium. Acta Endocrinologica 98(3): 446-450

Human myometrium was studied for specific binding of PGE2 and PGF2 alpha. PGF2 alpha-binding was almost undetectable, but specific binding sites for PGE2 with high affinity (KD = 2.7 +/- 0.4 x 10(-9) M were demonstrated. The binding capacity for PGE2 exhibited a topically different distribution pattern with the highest values in the central parts and low to undetectable levels in the cervical region. Binding characteristics were analyzed by receptor kinetics, revealing a homogeneous receptor population. Binding capacity in uteri obtained from post-menopausal women was of the order of 900-940 fmol/mg protein. Oestrogen pre-treatment and pregnancy were associated with a 3-fold reduction of the PGE2-binding capacity.


PMID: 6270944

Other references

Nazarenko I.V., 1971: Effect of formaldehyde on aquatic organisms. U S Government Research & Development Reports 71(5): 36

Foulds, E.; Grime, J.P., 1972: The influence of soil moisture on the frequency of cyano-genic plants in populations of Trifoliam repens and Lotus corniculatus. In soils exposed to drought there are fewer plants of T repens containing cyanogenic gluco-sides, and fewer plants of Lotus corniculatus containing beta -glucosidase, than occur in most soils A possible linkage is indicated between genes controlli...

Seneda, M.M.; Esper, C.R.; Garcia, J.M.; Oliveira, J.A. de; Vantini, R., 2001: Relationship between follicle size and ultrasound-guided transvaginal oocyte recovery. The relationship between follicle size and oocyte recovery (OR) was evaluated using ultrasound-guided follicle aspiration. Thirty Holstein cows were subjected to OR without gonadotrophic therapy. Oocytes were recovered two to four times from each...

Valentine J.T., 1979: Investigation for road rubble, District Council of Bute. Mineral Resources Review South Australia Department of Mines and Energy: Pages 93-96. 1979.

Hohenberger, G.M.; Berzins, U.; Bakota, B.; Holweg, P.; Clement, B.; Grechenig, S., 2017: Scaphoid screw placement under minimal radiation exposure. Percutaneous scaphoid fixation through either a volar or dorsal approach has the advantage of minor soft tissue damage compared with ORIF, and faster fracture union compared with conservative treatment. However, this technique demands highly intra...

Williams, DS., 1981: Daily changes in rhabdom structure and function in a locust. Proceedings of the Australian Physiological and Pharmacological Society, 122: 80p.

Pinney, E.; Mansbridge, J.N.; Sobin, S.S., 1998: Comparison of protein synthesis and secretion, and collagen deposition by human newborn dermal fibroblasts cultured in three dimensions and monolayer. FASEB Journal 12(5): A733, March 20

Gordon, N.F.; Cooper, K.H., 1988: Controlling cholesterol levels through exercise. Comprehensive Therapy 14(8): 52-57

Yuzbasheva, E.Y.; Mostova, E.B.; Andreeva, N.I.; Yuzbashev, T.V.; Laptev, I.A.; Sobolevskaya, T.I.; Sineoky, S.P., 2017: Co-expression of glucose-6-phosphate dehydrogenase and acyl-CoA binding protein enhances lipid accumulation in the yeast Yarrowia lipolytica. The oleaginous yeast Yarrowia lipolytica is a convenient model for investigating lipid biosynthesis and for engineering high lipid accumulated strains. In this organism, the pentose phosphate pathway is the major source of NADPH for lipid biosynth...

Ku, L.; Steinmetz, E.; Bruen, B.K., 2014: Continuous-eligibility policies stabilize Medicaid coverage for children and could be extended to adults with similar results. A key method of stabilizing Medicaid coverage is to provide beneficiaries with twelve months of continuous eligibility. Following the passage of the Children's Health Insurance Program Reauthorization Act in 2009, seven states adopted the con...