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Distribution of prostaglandin E2 and prostaglandin F2 alpha receptors in human myometrium


, : Distribution of prostaglandin E2 and prostaglandin F2 alpha receptors in human myometrium. Acta Endocrinologica 98(3): 446-450

Human myometrium was studied for specific binding of PGE2 and PGF2 alpha. PGF2 alpha-binding was almost undetectable, but specific binding sites for PGE2 with high affinity (KD = 2.7 +/- 0.4 x 10(-9) M were demonstrated. The binding capacity for PGE2 exhibited a topically different distribution pattern with the highest values in the central parts and low to undetectable levels in the cervical region. Binding characteristics were analyzed by receptor kinetics, revealing a homogeneous receptor population. Binding capacity in uteri obtained from post-menopausal women was of the order of 900-940 fmol/mg protein. Oestrogen pre-treatment and pregnancy were associated with a 3-fold reduction of the PGE2-binding capacity.

US$29.90

PMID: 6270944


Other references

Nazarenko I.V., 1971: Effect of formaldehyde on aquatic organisms. U S Government Research & Development Reports 71(5): 36

Foulds, E.; Grime, J.P., 1972: The influence of soil moisture on the frequency of cyano-genic plants in populations of Trifoliam repens and Lotus corniculatus. In soils exposed to drought there are fewer plants of T repens containing cyanogenic gluco-sides, and fewer plants of Lotus corniculatus containing beta -glucosidase, than occur in most soils A possible linkage is indicated between genes controlli...

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Valentine J.T., 1979: Investigation for road rubble, District Council of Bute. Mineral Resources Review South Australia Department of Mines and Energy: Pages 93-96. 1979.

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Williams, DS., 1981: Daily changes in rhabdom structure and function in a locust. Proceedings of the Australian Physiological and Pharmacological Society, 122: 80p.

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Gordon, N.F.; Cooper, K.H., 1988: Controlling cholesterol levels through exercise. Comprehensive Therapy 14(8): 52-57

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